Opening up heterochromatin by histone deacetylase inhibition improves response to DNA damage in lung cancer tumor initiating cells

被引:0
|
作者
Lundholm, Lovisa
Haag, Petra
Eriksson, Mina
Brzozowska, Beata
Lewensohn, Rolf
Wojcik, Andrzej
Viktorsson, Kristina
机构
关键词
D O I
10.1158/1538-7445.AM2016-3355
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3355
引用
收藏
页数:3
相关论文
共 50 条
  • [31] ERβ alters cell growth and the DNA damage response in lung cancer cells
    Nikolos, Fotis
    Rajapaksa, Gayani K.
    Thomas, Christoforos G.
    Gustafsson, Jan-Ake
    CANCER RESEARCH, 2011, 71
  • [32] Novel titanocene analogues induce apoptosis in prostate cancer epithelial cells by initiating a DNA damage response
    Cuffe, S.
    Dowling, C.
    Gill, C.
    Tacke, M.
    Fitzpatrick, J. M.
    Carty, M. P.
    Watson, R. W. G.
    EJC SUPPLEMENTS, 2008, 6 (09): : 29 - 29
  • [33] Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage
    Chang, Chi-Hsuan
    Zhang, Mei
    Rajapakshe, Kimal
    Coarfa, Cristian
    Edwards, Dean
    Huang, Shixia
    Rosen, Jeffrey M.
    STEM CELL REPORTS, 2015, 5 (03): : 378 - 391
  • [34] Histone deacetylase inhibition alters tumor phenotype and stimulates a productive anti-tumor immune response in preclinical models of ovarian cancer.
    McCaw, Tyler
    Turner, Taylor
    Smith, Haller M.
    Buchsbaum, Donald J.
    Randall, Troy
    Arend, Rebecca Christian
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [35] Histone demethyalase JMJD1A promotes the DNA damage response of prostate cancer cells
    Fan, Lingling
    Peng, Guihong
    Sahgal, Natasha
    Fazli, Ladan
    Gleave, Martin
    Zhang, Yuji
    Hussain, Arif
    Rassool, Feyruz
    Qi, Jianfei
    CANCER RESEARCH, 2016, 76
  • [36] A ROLE FOR HISTONE DEMETHYALASE JMJD1A IN THE DNA DAMAGE RESPONSE OF PROSTATE CANCER CELLS
    Fan, Lingling
    Peng, Guihong
    Sahgal, Natasha
    Fazli, Ladan
    Gleave, Martin
    Zhang, Yuji
    Hussain, Arif
    Rassool, Feyruz
    Qi, Jianfei
    JOURNAL OF UROLOGY, 2016, 195 (04): : E1146 - E1146
  • [37] Green tea polyphenols inhibit the growth and induce death of melanoma cells by initiating DNA damage and inhibition of class I histone deacetylases
    Prasad, Ram
    Katiyar, Santosh K.
    CANCER RESEARCH, 2014, 74 (19)
  • [38] Therapeutic AXL inhibition of tumor and tumor microenvironment stromal cells improves response to chemotherapy in ovarian cancer
    Mullen, M. M.
    Lomonosova, E.
    Beck-Noia, H.
    Wilke, D.
    Guo, L.
    Hagemann, A. R.
    Kuroki, L. M.
    McCourt, C. K.
    Thaker, P. H.
    Mutch, D. G.
    Powell, M. A.
    Fuh, K. C.
    GYNECOLOGIC ONCOLOGY, 2019, 154 : 35 - 35
  • [39] Analysis of Chromatin Opening in Heterochromatic Non-Small Cell Lung Cancer Tumor-Initiating Cells in Relation to DNA-Damaging Antitumor Treatment
    Eriksson, Mina
    Haag, Petra
    Brzozowska, Beata
    Lipka, Magdalena
    Lisowska, Halina
    Lewensohn, Rolf
    Wojcik, Andrzej
    Viktorsson, Kristina
    Lundholm, Lovisa
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 100 (01): : 174 - 187
  • [40] Notch pathway inhibition mediated by arsenic trioxide depletes tumor initiating cells in small cell lung cancer
    Meng-Hang Yang
    Bing Li
    Ke-Jie Chang
    Molecular Biology Reports, 2022, 49 : 2245 - 2253