Therapeutic AXL inhibition of tumor and tumor microenvironment stromal cells improves response to chemotherapy in ovarian cancer

被引:1
|
作者
Mullen, M. M. [1 ]
Lomonosova, E. [1 ]
Beck-Noia, H. [1 ]
Wilke, D. [1 ]
Guo, L. [1 ]
Hagemann, A. R. [1 ]
Kuroki, L. M. [1 ]
McCourt, C. K. [2 ]
Thaker, P. H. [1 ]
Mutch, D. G. [1 ]
Powell, M. A. [1 ]
Fuh, K. C. [1 ]
机构
[1] Washington Univ, Sch Med St Louis, St Louis, MO 63110 USA
[2] Brown Univ, Women & Infants Hosp, Providence, RI USA
关键词
D O I
10.1016/j.ygyno.2019.04.083
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
68
引用
收藏
页码:35 / 35
页数:1
相关论文
共 50 条
  • [1] Effect of therapeutic GAS6/AXL inhibition of tumor and stromal cells on DNA damage and response to chemotherapy in ovarian cancer.
    Mullen, Mary M.
    Lomonosova, Elena
    Noia, Hollie M.
    Guo, Lei
    Kuroki, Lindsay Midori
    Hagemann, Andrea M.
    McCourt, Carolyn K.
    Thaker, Premal H.
    Mutch, David Gardner
    Powell, Matthew A.
    Fuh, Katherine Cynthia
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [2] Tumor and stromal AXL expression regulate ovarian cancer metastasis
    Mullen, Mary Margaret
    van Biljon, Lillian N.
    Quinn, Jeanne
    Greenwade, Molly
    Opara, Gregory
    Noia, Hollie
    Hagemann, Ian S.
    Hagemann, Andrea R.
    Kuroki, Lindsay M.
    McCourt, Carolyn K.
    Thaker, Premal H.
    Powell, Matthew A.
    Mutch, David G.
    Khabele, Dineo
    Fuh, Katherine C.
    [J]. CANCER RESEARCH, 2022, 82 (12)
  • [3] Tumor and Stromal AXL Expression Regulate Ovarian Cancer Metastasis
    Mullen, Mary M.
    Van Biljon, Lillian N.
    Quinn, Jeanne
    Greenwade, Molly
    Opara, Gregory
    Noia, Hollie
    Hagemann, Ian S.
    Hagemann, Andrea R.
    Kuroki, Lindsay M.
    McCourt, Carolyn K.
    Thaker, Premal H.
    Powell, Matthew A.
    Mutch, David G.
    Khabele, Dineo
    Fuh, Katherine C.
    [J]. REPRODUCTIVE SCIENCES, 2022, 29 (SUPPL 1) : 97 - 98
  • [4] BROMODOMAIN INHIBITION IN OVARIAN CANCER AND THE TUMOR MICROENVIRONMENT
    Wilson, Andrew J.
    Hoover, Alyssa
    Harris, Whitney
    Liu, Esther
    Khabele, Dineo
    Yull, Fiona E.
    [J]. CLINICAL CANCER RESEARCH, 2019, 25 (22) : 172 - 172
  • [5] Stromal cells in tumor microenvironment and breast cancer
    Yan Mao
    Evan T. Keller
    David H. Garfield
    Kunwei Shen
    Jianhua Wang
    [J]. Cancer and Metastasis Reviews, 2013, 32 : 303 - 315
  • [6] Stromal cells in tumor microenvironment and breast cancer
    Mao, Yan
    Keller, Evan T.
    Garfield, David H.
    Shen, Kunwei
    Wang, Jianhua
    [J]. CANCER AND METASTASIS REVIEWS, 2013, 32 (1-2) : 303 - 315
  • [7] Hampering Stromal Cells in the Tumor Microenvironment as a Therapeutic Strategy to Destem Cancer Stem Cells
    Chung, Katherine Po Sin
    Leung, Rainbow Wing Hei
    Lee, Terence Kin Wah
    [J]. CANCERS, 2021, 13 (13)
  • [8] Tumor Microenvironment in Ovarian Cancer: Function and Therapeutic Strategy
    Yang, Yanfei
    Yang, Yang
    Yang, Jing
    Zhao, Xia
    Wei, Xiawei
    [J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
  • [9] Chemotherapy-induced microenvironment of ovarian cancer cells promotes tumor resistance
    Shender, V.
    Shnaider, P.
    Anufrieva, K.
    Pavlyukov, M.
    Arapidi, G.
    Lagarkova, M.
    Govorun, V.
    [J]. FEBS OPEN BIO, 2018, 8 : 329 - 329
  • [10] Bromodomain inhibition in ovarian cancer and the tumor microenvironment to improve PARP inhibitor response
    Wilson, Andrew J.
    Hoover, Alyssa
    Harris, Whitney
    Liu, Esther
    Khabele, Dineo
    Yull, Fiona
    [J]. CANCER RESEARCH, 2018, 78 (13)