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Terephthalaldehyde: An Effecient Key Precursor for Novel Synthesis of Some Interesting Bis-thiazoles and Bis-triazolopyrimidinones
被引:11
|作者:
Gomha, Sobhi M.
[1
]
Farghaly, Thoraya A.
[1
,2
]
Abbas, Eman M. H.
[3
]
Alqurashi, Nadia T.
[2
]
机构:
[1] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt
[2] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Makkah El Mukarramah, Saudi Arabia
[3] Natl Res Ctr, Dept Chem Natl & Microbial Prod, Cairo, Egypt
关键词:
BIOLOGICAL-ACTIVITY;
HYDRAZONOYL HALIDES;
FUSED HETEROCYCLES;
MOLECULAR DOCKING;
DERIVATIVES;
INHIBITORS;
AGENTS;
D O I:
10.1002/jhet.3100
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
Novel bis-thiazoles were synthesized in high and efficient yields from the reaction of thiosemicarbazones with halogenated compounds. Also, new bis-triazolopyrimidines were prepared from the reaction of hydrazonoyl chlorides with bis-thione derivative. All prepared compounds were fully characterized by spectral methods. The synthesized bis-compounds will be attractive species for the medicinal researchers to investigate their biological activity.
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页码:750 / 755
页数:6
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