Terephthalaldehyde: An Effecient Key Precursor for Novel Synthesis of Some Interesting Bis-thiazoles and Bis-triazolopyrimidinones

被引：11

作者：

Gomha, Sobhi M. ^{[1
]}

Farghaly, Thoraya A. ^{[1
,2
]}

Abbas, Eman M. H. ^{[3
]}

Alqurashi, Nadia T. ^{[2
]}

机构：

[1] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt

[2] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Makkah El Mukarramah, Saudi Arabia

[3] Natl Res Ctr, Dept Chem Natl & Microbial Prod, Cairo, Egypt

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2018年 / 55卷 / 03期

关键词：

BIOLOGICAL-ACTIVITY; HYDRAZONOYL HALIDES; FUSED HETEROCYCLES; MOLECULAR DOCKING; DERIVATIVES; INHIBITORS; AGENTS;

D O I：

10.1002/jhet.3100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel bis-thiazoles were synthesized in high and efficient yields from the reaction of thiosemicarbazones with halogenated compounds. Also, new bis-triazolopyrimidines were prepared from the reaction of hydrazonoyl chlorides with bis-thione derivative. All prepared compounds were fully characterized by spectral methods. The synthesized bis-compounds will be attractive species for the medicinal researchers to investigate their biological activity.

引用

页码：750 / 755

页数：6

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