"Turn-On" Fluorescent Probe for Hypochlorite: Successful Bioimaging and Real Application in Tap Water

被引：2

作者：

Cheng, Xiaohong ^{[1
]}

Li, Shuang ^{[2
]}

Wang, Jingyanga ^{[1
]}

Li, Wangnan ^{[1
]}

机构：

[1] Hubei Univ Arts & Sci, Hubei Key Lab Low Dimens Optoelect Mat & Devices, Xiangyang 441053, Hubei, Peoples R China

[2] Hubei Inst Aerosp Chem Technol, Xiangyang 441003, Hubei, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 40卷 / 07期

关键词：

fluorescent probe; hypochlorite; good solubility; bioimaging application; AGGREGATION-INDUCED EMISSION; SELECTIVE DETECTION; ACID DETECTION; C=N ISOMERIZATION; AQUEOUS-SOLUTION; LIGHT-EMISSION; CHEMOSENSOR; AL3+; ION;

D O I：

10.6023/cjoc202003034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Taking advantage of the special oxidation property of hypochlorite, two novel coumarin-type fluorescent probes C1 and C2 were synthesized for ClO- detection. Both probes could detect ClO- anions in aqueous solution efficiently with rapid switching-on fluorescent methods. Especially, probe C2 displayed dramatic enhancement in fluorescence emission spectra with the detection limit of 1.8 x 10(-7) mol/L. In addition to its high selectivity for ClO- rather than other common anions and reactive oxygen species, C2 was successfully applied to the bioimaging in HeLa cells with 'turn-on' fluorescent methods. Moreover, probe C2 could be used for the analysis of ClO- levels in tap water and potentially in environmental samples.

引用

页码：1941 / 1947

页数：7

共 46 条

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