"Turn-On" Fluorescent Probe for Hypochlorite: Successful Bioimaging and Real Application in Tap Water

被引：2
|
作者：
Cheng, Xiaohong [1 ]
Li, Shuang [2 ]
Wang, Jingyanga [1 ]
Li, Wangnan [1 ]
机构：
[1] Hubei Univ Arts & Sci, Hubei Key Lab Low Dimens Optoelect Mat & Devices, Xiangyang 441053, Hubei, Peoples R China
[2] Hubei Inst Aerosp Chem Technol, Xiangyang 441003, Hubei, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 40卷 / 07期
关键词：
fluorescent probe; hypochlorite; good solubility; bioimaging application; AGGREGATION-INDUCED EMISSION; SELECTIVE DETECTION; ACID DETECTION; C=N ISOMERIZATION; AQUEOUS-SOLUTION; LIGHT-EMISSION; CHEMOSENSOR; AL3+; ION;
D O I：
10.6023/cjoc202003034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Taking advantage of the special oxidation property of hypochlorite, two novel coumarin-type fluorescent probes C1 and C2 were synthesized for ClO- detection. Both probes could detect ClO- anions in aqueous solution efficiently with rapid switching-on fluorescent methods. Especially, probe C2 displayed dramatic enhancement in fluorescence emission spectra with the detection limit of 1.8 x 10(-7) mol/L. In addition to its high selectivity for ClO- rather than other common anions and reactive oxygen species, C2 was successfully applied to the bioimaging in HeLa cells with 'turn-on' fluorescent methods. Moreover, probe C2 could be used for the analysis of ClO- levels in tap water and potentially in environmental samples.
引用
收藏
页码：1941 / 1947
页数：7
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