Solution of Equations Based on Analog DNA Strand Displacement Circuits

被引：25
|
作者：
Zou, Chengye [1 ]
Wei, Xiaopeng [1 ]
Zhang, Qiang [1 ,2 ]
Liu, Chanjuan [1 ]
Liu, Yuan [1 ]
机构：
[1] Dalian Univ Technol, Fac Elect Informat & Elect Engn, Dalian 116024, Peoples R China
[2] Dalian Univ, Minist Educ, Key Lab Adv & Intelligent Comp, Dalian 116622, Peoples R China
来源：
IEEE TRANSACTIONS ON NANOBIOSCIENCE | 2019年 / 18卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Analog circuits; chemical reaction networks; DNA strand displacement; reaction modules; LOGIC MODEL; COMPUTATION; AMPLIFICATION; DESIGN; GATE;
D O I：
10.1109/TNB.2019.2897116
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Deoxyribonucleic acid (DNA) strand displacement can be used to build complex functional circuits due to its highly modular and programmable properties. While DNA strand displacement is most often used to solve logic problems, it can also be used to compute the roots of equations. In this paper, we present the design of novel architectures for catalysis, degradation, and annihilation in ideal formal reaction modules, and we translate these reaction modules to DNA networks. These ideal formal or DNA reaction modules are suitable for building analog circuits for solving tasks. The computing analog DNA circuits are assessed by solving a linear equation, a one-variable quadratic equation, and a set of two simultaneous linear equations. The results were evaluated by simulation.
引用
收藏
页码：191 / 204
页数：14
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