Modeling the Drug Release From 3D Multi-layer Microstructure with Micro-chambers

被引：0

作者：

Yu, Ruixia ^{[1
]}

Chen, Hualing ^{[1
]}

Chen, Tianning ^{[1
]}

Zhou, Xiangyang ^{[2
]}

机构：

[1] Xi An Jiao Tong Univ, Sch Mech Engn, Xian 710049, Peoples R China

[2] Xi An Jiao Tong Univ, Inst Precis Engn, Xian 710049, Peoples R China

来源：

2007 7TH IEEE CONFERENCE ON NANOTECHNOLOGY, VOL 1-3 | 2007年

关键词：

Modeling; Cellular automata (CA); Biodegradable polymer; Multi-layer drug delivery microstructure; Three dimensions;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper presents a mathematical model for three-dimensional biodegradable multi-layer drug delivery microstructure with large array of micro-chambers. The simultaneous release of multiple drugs from this type of drug delivery microstructure is modeled using cellular automata (CA) and discrete iterations. The model can describe the dynamic behavior of drug release. Furthermore, simulations about this type of drug delivery microstructure enclosed two drugs are carried out. The simulation results show that the introduced mathematical model can act as the basis of a new optimal design methodology for three-dimensional biodegradable multi-layer drug delivery microstructure.

引用

页码：562 / +

页数：2

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