Spectrophotometric Determination of Gemifloxacin in Bulk and Pharmaceutical Formulation

被引：0
|
作者：
Ganapathy, S. [1 ]
Raju, G. V. H. [1 ]
Sankar, D. G. [1 ]
Naidu, Pettla Y. [1 ]
机构：
[1] Andhra Univ, Dept Pharmaceut Sci, Visakhapatnam 530003, Andhra Pradesh, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2009年 / 21卷 / 08期
关键词：
Spectrophotometry; Gemifloxacin; PERFORMANCE LIQUID-CHROMATOGRAPHY; HUMAN PLASMA; SEPARATION;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A three simple, sensitive and reproducible visible spectrophotometric methods (methods A-C) are developed for the determination of gemifloxacin in pure and dosage forms. Method A is based on the formation of coloured species on treatment of reduced gemifloxacin with Folin-Ciocalteu reagent in presence of 4 % NaOH solution. Method B is based on the formation of coloured species on treatment of gemifloxacin with 3-methyl-2-benzo thiazolinone hydrazone and ferric chloride. Method C is based on the formation of coloured species on treatment of gemifloxacin with FeCl3 and 1,10-phenanthorline.
引用
收藏
页码：6508 / 6512
页数：5
相关论文
共 50 条
  • [41] Spectrophotometric determination of rabeprazole sodium in bulk and tablet formulation
    Gosavi, S. A.
    Shirkhedkar, A. A.
    Surana, S. J.
    ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (06) : 4928 - 4930
  • [42] Spectrophotometric Determination of Valdecoxib from Bulk Drug and Formulation
    Baviskar, D. T.
    Jagdale, S. C.
    Girase, N. O.
    Deshpande, A. Y.
    Jain, D. K.
    ASIAN JOURNAL OF CHEMISTRY, 2009, 21 (01) : 206 - 210
  • [43] Development and validation of a spectrophotometric method for estimation of letrozole in bulk and pharmaceutical formulation
    Mondal, N.
    Pal, T. K.
    Ghosal, S. K.
    PHARMAZIE, 2007, 62 (08): : 597 - 598
  • [44] Spectrophotometric Determination of Gemifloxacin Mesylate, Moxifloxacin. HCl and Gatifloxacin Sesquihydrate in Pure and in Pharmaceutical Preparations
    Zayed, M. A.
    Dakhly, Heba A.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2015, 58 (03): : 349 - 364
  • [45] Validated UV-Spectrophotometric Methods for Determination of Gemifloxacin Mesylate in Pharmaceutical Tablet Dosage Forms
    Ambadas, R. Rote
    Sunita, P. Pingle
    E-JOURNAL OF CHEMISTRY, 2010, 7 : S344 - S348
  • [46] Spectrophotometric Determination of Gemifloxacin Mesylate, Moxifloxacin Hydrochloride, and Enrofloxacin in Pharmaceutical Formulations Using Acid Dyes
    Gouda, Ayman A.
    Amin, Alaa S.
    El-Sheikh, Ragaa
    Yousef, Amira G.
    JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY, 2014, 2014
  • [47] Spectrophotometric Determination of Gemifloxacin Mesylate in Pharmaceutical Formulations Through Ion-Pair Complex Formation
    Krishna, Marothu Vamsi
    Sankar, Dannana Gowri
    E-JOURNAL OF CHEMISTRY, 2008, 5 (03) : 515 - 520
  • [48] Spectrophotometric determination of meloxicam by sodium nitroprusside and 1,10-phenanthroline reagents in bulk and its pharmaceutical formulation
    Gurupadayya, B. M.
    Trinath, M. N.
    Shilpa, K.
    INDIAN JOURNAL OF CHEMICAL TECHNOLOGY, 2013, 20 (02) : 111 - 115
  • [49] UV spectrophotometric determination of cefpodoxime proxetil in pure and pharmaceutical formulation
    Chauhan, C. S.
    Ranawat, M. S.
    Choudhury, P. K.
    ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (04) : 3277 - 3279
  • [50] Spectrophotometric and spectrofluorimetric methods for the determination of tranexamic acid in pharmaceutical formulation
    El-Aroud, Khalifa Abulghasem
    Abushoffa, Adel Mohamed
    Abdellatef, Hisham Ezzat
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (03) : 364 - 367
12345