Spectrophotometric Determination of Gemifloxacin in Bulk and Pharmaceutical Formulation

被引：0
|
作者：
Ganapathy, S. [1 ]
Raju, G. V. H. [1 ]
Sankar, D. G. [1 ]
Naidu, Pettla Y. [1 ]
机构：
[1] Andhra Univ, Dept Pharmaceut Sci, Visakhapatnam 530003, Andhra Pradesh, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2009年 / 21卷 / 08期
关键词：
Spectrophotometry; Gemifloxacin; PERFORMANCE LIQUID-CHROMATOGRAPHY; HUMAN PLASMA; SEPARATION;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A three simple, sensitive and reproducible visible spectrophotometric methods (methods A-C) are developed for the determination of gemifloxacin in pure and dosage forms. Method A is based on the formation of coloured species on treatment of reduced gemifloxacin with Folin-Ciocalteu reagent in presence of 4 % NaOH solution. Method B is based on the formation of coloured species on treatment of gemifloxacin with 3-methyl-2-benzo thiazolinone hydrazone and ferric chloride. Method C is based on the formation of coloured species on treatment of gemifloxacin with FeCl3 and 1,10-phenanthorline.
引用
收藏
页码：6508 / 6512
页数：5
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