Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

被引：0
|
作者：
Lin, Li-Chun [1 ]
Kavala, Veerababurao [1 ]
Ichake, Sachin [1 ]
Yao, Ching-Fa [1 ]
机构：
[1] Natl Taiwan Normal Univ, Dept Chem, 88,Sec4,Ting Zhou Rd, Taipei 11677, Taiwan
来源：
CHEMISTRYSELECT | 2023年 / 8卷 / 33期
关键词：
Copper catalyst; 2-Iodobenzamides; Isoindolo[1,2-b]quinazolin-12(10H)-ones; One-Pot; Tandem Cyclization; BATRACYLIN NSC-320846; NATURAL-PRODUCTS; CYCLIZATION;
D O I：
10.1002/slct.202302052
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.
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页数：4
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