Synthesis of Isoindolo [1,2-b]quinazolin-12(10H)-one by Double Ullman reaction of 2-Iodobenzamides with Copper Cyanide under Microwave Irradiation

被引：0

作者：

Lin, Li-Chun ^{[1
]}

Kavala, Veerababurao ^{[1
]}

Ichake, Sachin ^{[1
]}

Yao, Ching-Fa ^{[1
]}

机构：

[1] Natl Taiwan Normal Univ, Dept Chem, 88,Sec4,Ting Zhou Rd, Taipei 11677, Taiwan

来源：

CHEMISTRYSELECT | 2023年 / 8卷 / 33期

关键词：

Copper catalyst; 2-Iodobenzamides; Isoindolo[1,2-b]quinazolin-12(10H)-ones; One-Pot; Tandem Cyclization; BATRACYLIN NSC-320846; NATURAL-PRODUCTS; CYCLIZATION;

D O I：

10.1002/slct.202302052

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and one-pot method for the synthesis of isoindolo [1,2-b]quinazolin-12(10H)-one derivative via copper-catalyzed tandem reaction of N-(2-bromobenzyl)-2-iodobenzamide as substrate and copper cyanide is developed under microwave irradiation. The procedure is easy and simple and the yields are good to excellent.

引用

页数：4

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