Two new terpenoid glycosides from Isodon macrocalyx

被引：2
|
作者：
Liang, Xiaoqin [1 ]
Chang, Yanling [1 ]
Guan, Xinlan [2 ]
Huang, Yan [1 ]
Pan, Liwei [1 ]
Li, Jun [1 ]
Li, Jian [2 ]
机构：
[1] Guangxi Normal Univ, Collaborat Innovat Ctr Guangxi Ethn Med, Sch Chem & Pharmaceut Sci, State Key Lab Chem & Mol Engn Med Resources, Guilin, Peoples R China
[2] Peoples Hosp Pubei, Pubei, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2024年 / 38卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Isodon macrocalyx; Lamiaceae; macrocalyxoside A; macrocalyxoside B; anti-HBV; DITERPENOIDS; APOPTOSIS; EXCISUS;
D O I：
10.1080/14786419.2022.2113997
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
One previously undescribed tricyclo-diterpenoid saponin (1), one undescribed dammarane triterpenoid saponin (2) and four known triterpenoids (3-6) were isolated from the aerial part of Isodon macrocalyx. Their structures were determined using 1 D- and 2 D-NMR, HRESIMS, and comparison of their spectroscopic data with previously reported data. The isolates were evaluated for their anti-HBV activity in vitro using the HBV transfected Hep G2.2.15 cell line. Compounds 2 and 3 exhibited moderate anti-HBV activity.
引用
收藏
页码：220 / 226
页数：7
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