New terpenoid glycosides obtained from Rosmarinus officinalis L. aerial parts

被引:20
|
作者
Zhang, Yi [1 ]
Adelakun, Tiwalade Adegoke [2 ,3 ]
Qu, Lu [2 ,3 ]
Li, Xiaoxia [2 ,3 ]
Li, Jian [2 ,3 ]
Han, Lifeng [1 ,2 ,3 ]
Wang, Tao [1 ,2 ,3 ]
机构
[1] Tianjin State Key Lab Modern Chinese Med, Tianjin 300193, Peoples R China
[2] Tianjin Univ Tradit Chinese Med, Tianjin Key Lab TCM Chem & Anal, Tianjin 300193, Peoples R China
[3] Tianjin Univ Tradit Chinese Med, Inst Tradit Chinese Med, Tianjin 300193, Peoples R China
关键词
Rosmarinus officinalis; Terpenoid glycosides; Normonoterpenoid; Diterpenoid; Triterpenoid; TRITERPENE SAPONINS; IN-VIVO; CONSTITUENTS; ROSEMARY; SAGE; SEEDS;
D O I
10.1016/j.fitote.2014.09.004
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Five new terpenoid glycosides, named as officinoterpenosides A(1) (1), A(2) (2), B (3), C (4), and D (5), together with 11 known ones, (1S,4S,5S)-5-exo-hydrocamphor 5-O-beta-D-glucopyranoside (6), isorosmanol (7), rosmanol (8), 7-methoxyrosmanol (9), epirosmanol (10), ursolic acid (11), micromeric acid (12), oleanolic acid (13), niga-ichigoside F-1 (14), glucosyl tormentate (15), and asteryunnanoside B (16), were obtained from the aerial parts of Rosmarinus officinalis L Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Among the new ones, land 2,3 and 4 are diterpenoid and triterpenoid glycosides, respectively; and 5 is a normonoterpenoid. For the known ones, 6 was isolated from the Rosmarinus genus first, and 15, 16 were obtained from this species for the first time. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:78 / 85
页数:8
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