The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partners Scientific Board (PPSB)

被引:2
|
作者
Albala, Bruce [1 ,14 ,15 ]
Appelmans, Eline [2 ]
Burress, Ramona [3 ,16 ]
De Santi, Susan [1 ,4 ,17 ]
Devins, Theresa [1 ,18 ]
Klein, Gregory [5 ]
Logovinsky, Veronika [1 ,19 ]
Novak, Gerald P. [3 ]
Ribeiro, Kim [6 ]
Schmidt, Mark E. [7 ]
Schwarz, Adam J. [8 ]
Scott, David [9 ]
Shcherbinin, Sergey [10 ]
Siemers, Eric [11 ]
Travaglia, Alessio [2 ]
Weber, Christopher J. [12 ]
White, Leah [2 ,20 ]
Wolf-Rodda, Julie [2 ]
Vasanthakumar, Aparna [6 ,13 ]
机构
[1] Eisai Inc, Nutley, NJ USA
[2] Fdn Natl Inst Hlth, North Bethesda, MD USA
[3] Janssen Res & Dev LLC, Titusville, NJ USA
[4] Life Mol Imaging, Berlin, Germany
[5] F Hoffmann La Roche Ltd, Basel, Switzerland
[6] AbbVie Inc, N Chicago, IL USA
[7] Janssen Res & Dev, Beerse, Belgium
[8] Takeda Pharmaceut Co Ltd, Cambridge, MA USA
[9] Clario, San Mateo, CA USA
[10] Eli Lilly & Co, Indianapolis, IN USA
[11] Cogstate Ltd, New Haven, CT USA
[12] Alzheimers Assoc, Chicago, IL USA
[13] Abbvie, Genom Res Ctr, 1 N Waukegan Rd, N Chicago, IL 60064 USA
[14] Univ Calif Irvine, Program Publ Hlth, 856 Hlth Sci Quad, Irvine, CA 92697 USA
[15] Univ Calif Irvine, UCI Sch Med, Dept Neurol, 856 Hlth Sci Quad, Irvine, CA 92697 USA
[16] Takeda, 95 Hayden Ave, Lexington, MA 02421 USA
[17] Eisai Inc, Nutley, NJ USA
[18] Cognit Therapeut, 2500 Westchester Ave, Purchase, NY 10577 USA
[19] Lundbeck, 6 Pkwy N, Deerfield, IL 60015 USA
[20] Veranex, 5420 Wade Pk Blvd,Suite 204, Raleigh, NC 27607 USA
基金
美国国家卫生研究院; 加拿大健康研究院;
关键词
Alzheimer's disease clinical trials; Alzheimer's Disease Neuroimaging Initiative; biomarkers; neuroimaging; COGSTATE BRIEF BATTERY; FINANCIAL CAPACITY; DEMENTIA; MEMORY; BIOMARKERS; SCALE; ANK1; MCI;
D O I
10.1002/alz.13483
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partners Scientific Board (PPSB) encompasses members from industry, biotechnology, diagnostic, and non-profit organizations that have until recently been managed by the Foundation for the National Institutes of Health (FNIH) and provided financial and scientific support to ADNI programs. In this article, we review some of the major activities undertaken by the PPSB, focusing on those supporting the most recently completed National Institute on Aging grant, ADNI3, and the impact it has had on streamlining biomarker discovery and validation in Alzheimer's disease. We also provide a perspective on the gaps that may be filled with future PPSB activities as part of ADNI4 and beyond.
引用
收藏
页码:695 / 708
页数:14
相关论文
共 50 条
  • [41] Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects
    Trojanowski, John Q.
    Vandeerstichele, Hugo
    Korecka, Magdalena
    Clark, Christopher M.
    Aisen, Paul S.
    Petersen, Ronald C.
    Blennow, Kaj
    Soares, Holly
    Simon, Adam
    Lewczuk, Piotr
    Dean, Robert
    Siemers, Eric
    Potter, William Z.
    Weiner, Michael W.
    Jack, Clifford R., Jr.
    Jagust, William
    Toga, Arthur W.
    Lee, Virginia M. -Y.
    Shaw, Leslie M.
    ALZHEIMERS & DEMENTIA, 2010, 6 (03) : 230 - 238
  • [42] A Focus on Structural Brain Imaging in the Alzheimer's Disease Neuroimaging Initiative
    Braskie, Meredith N.
    Thompson, Paul M.
    BIOLOGICAL PSYCHIATRY, 2014, 75 (07) : 527 - 533
  • [43] Progression of Alzheimer's Disease by Self-Reported Cancer History in the Alzheimer's Disease Neuroimaging Initiative
    Fowler, Mackenzie E.
    Triebel, Kristen L.
    Cutter, Gary R.
    Schneider, Lon S.
    Kennedy, Richard E.
    JOURNAL OF ALZHEIMERS DISEASE, 2020, 76 (02) : 691 - 701
  • [44] Total Cholesterol and APOE-Related Risk for Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative
    Dunk, Michelle M.
    Driscoll, Ira
    JOURNAL OF ALZHEIMERS DISEASE, 2022, 85 (04) : 1519 - 1528
  • [45] Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease
    Veitch, Dallas P.
    Weiner, Michael W.
    Aisen, Paul S.
    Beckett, Laurel A.
    DeCarli, Charles
    Green, Robert C.
    Harvey, Danielle
    Jack, Clifford R., Jr.
    Jagust, William
    Landau, Susan M.
    Morris, John C.
    Okonkwo, Ozioma
    Perrin, Richard J.
    Petersen, Ronald C.
    Rivera-Mindt, Monica
    Saykin, Andrew J.
    Shaw, Leslie M.
    Toga, Arthur W.
    Tosun, Duygu
    Trojanowski, John Q.
    ALZHEIMERS & DEMENTIA, 2022, 18 (04) : 824 - 857
  • [46] Biomarkers of Alzheimer's disease in Black and/or African American Alzheimer's Disease Neuroimaging Initiative (ADNI) participants
    Groechel, Renee C.
    Tripodis, Yorghos
    Alosco, Michael L.
    Mez, Jesse
    Qiu, Wei Qiao
    Goldstein, Lee
    Budson, Andrew E.
    Kowall, Neil W.
    Shaw, Leslie M.
    Weiner, Michael
    Jack, Clifford R., Jr.
    Killiany, R. J.
    NEUROBIOLOGY OF AGING, 2023, 131 : 144 - 152
  • [47] Biomarkers and phenotypic expression in Alzheimer's disease: exploring the contribution of frailty in the Alzheimer's Disease Neuroimaging Initiative
    Canevelli, Marco
    Arisi, Ivan
    Bacigalupo, Ilaria
    Arighi, Andrea
    Galimberti, Daniela
    Vanacore, Nicola
    D'Onofrio, Mara
    Cesari, Matteo
    Bruno, Giuseppe
    GEROSCIENCE, 2021, 43 (02) : 1039 - 1051
  • [48] Clusters of male and female Alzheimer’s disease patients in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database
    Gamberger D.
    Ženko B.
    Mitelpunkt A.
    Shachar N.
    Lavrač N.
    Brain Informatics, 2016, 3 (3) : 169 - 179
  • [49] Biomarkers and phenotypic expression in Alzheimer’s disease: exploring the contribution of frailty in the Alzheimer’s Disease Neuroimaging Initiative
    Marco Canevelli
    Ivan Arisi
    Ilaria Bacigalupo
    Andrea Arighi
    Daniela Galimberti
    Nicola Vanacore
    Mara D’Onofrio
    Matteo Cesari
    Giuseppe Bruno
    GeroScience, 2021, 43 : 1039 - 1051
  • [50] Introduction to special issue: Overview of Alzheimer's Disease Neuroimaging Initiative
    Weiner, Michael W.
    Veitch, Dallas P.
    ALZHEIMERS & DEMENTIA, 2015, 11 (07) : 730 - 733