The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partners Scientific Board (PPSB)

被引：2

作者：

Albala, Bruce ^{[1
,14
,15
]}

Appelmans, Eline ^{[2
]}

Burress, Ramona ^{[3
,16
]}

De Santi, Susan ^{[1
,4
,17
]}

Devins, Theresa ^{[1
,18
]}

Klein, Gregory ^{[5
]}

Logovinsky, Veronika ^{[1
,19
]}

Novak, Gerald P. ^{[3
]}

Ribeiro, Kim ^{[6
]}

Schmidt, Mark E. ^{[7
]}

Schwarz, Adam J. ^{[8
]}

Scott, David ^{[9
]}

Shcherbinin, Sergey ^{[10
]}

Siemers, Eric ^{[11
]}

Travaglia, Alessio ^{[2
]}

Weber, Christopher J. ^{[12
]}

White, Leah ^{[2
,20
]}

Wolf-Rodda, Julie ^{[2
]}

Vasanthakumar, Aparna ^{[6
,13
]}

机构：

[1] Eisai Inc, Nutley, NJ USA

[2] Fdn Natl Inst Hlth, North Bethesda, MD USA

[3] Janssen Res & Dev LLC, Titusville, NJ USA

[4] Life Mol Imaging, Berlin, Germany

[5] F Hoffmann La Roche Ltd, Basel, Switzerland

[6] AbbVie Inc, N Chicago, IL USA

[7] Janssen Res & Dev, Beerse, Belgium

[8] Takeda Pharmaceut Co Ltd, Cambridge, MA USA

[9] Clario, San Mateo, CA USA

[10] Eli Lilly & Co, Indianapolis, IN USA

[11] Cogstate Ltd, New Haven, CT USA

[12] Alzheimers Assoc, Chicago, IL USA

[13] Abbvie, Genom Res Ctr, 1 N Waukegan Rd, N Chicago, IL 60064 USA

[14] Univ Calif Irvine, Program Publ Hlth, 856 Hlth Sci Quad, Irvine, CA 92697 USA

[15] Univ Calif Irvine, UCI Sch Med, Dept Neurol, 856 Hlth Sci Quad, Irvine, CA 92697 USA

[16] Takeda, 95 Hayden Ave, Lexington, MA 02421 USA

[17] Eisai Inc, Nutley, NJ USA

[18] Cognit Therapeut, 2500 Westchester Ave, Purchase, NY 10577 USA

[19] Lundbeck, 6 Pkwy N, Deerfield, IL 60015 USA

[20] Veranex, 5420 Wade Pk Blvd,Suite 204, Raleigh, NC 27607 USA

来源：

ALZHEIMERS & DEMENTIA | 2024年 / 20卷 / 01期

基金：

美国国家卫生研究院; 加拿大健康研究院;

关键词：

Alzheimer's disease clinical trials; Alzheimer's Disease Neuroimaging Initiative; biomarkers; neuroimaging; COGSTATE BRIEF BATTERY; FINANCIAL CAPACITY; DEMENTIA; MEMORY; BIOMARKERS; SCALE; ANK1; MCI;

D O I：

10.1002/alz.13483

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partners Scientific Board (PPSB) encompasses members from industry, biotechnology, diagnostic, and non-profit organizations that have until recently been managed by the Foundation for the National Institutes of Health (FNIH) and provided financial and scientific support to ADNI programs. In this article, we review some of the major activities undertaken by the PPSB, focusing on those supporting the most recently completed National Institute on Aging grant, ADNI3, and the impact it has had on streamlining biomarker discovery and validation in Alzheimer's disease. We also provide a perspective on the gaps that may be filled with future PPSB activities as part of ADNI4 and beyond.

引用

页码：695 / 708

页数：14

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