Targeting the Cell Cycle Checkpoints CHK1 and CHK2 is a Novel Therapeutic Approach for Pediatric Neuroblastoma

被引：0
|
作者：
Morrison, Ben [1 ]
Chilamakuri, Rameswari [1 ]
Agarwal, Saurabh
机构：
[1] St Johns Univ, Jamaica, NY 11439 USA
来源：
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS | 2023年 / 385卷
关键词：
D O I：
10.1124/jpet.122.230730
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
49
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Expression, activation and clinical relevance of CHK1 and CHK2 in metastatic high-grade serous carcinoma
    Davidson, Ben
    Bjornerem, Marianne
    Holth, Arild
    Hellesylt, Ellen
    Falkenthal, Thea E. Hetland
    Florenes, Vivi Ann
    GYNECOLOGIC ONCOLOGY, 2018, 150 (01) : 136 - 142
  • [42] PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
    Lu, XB
    Nannenga, B
    Donehower, LA
    GENES & DEVELOPMENT, 2005, 19 (10) : 1162 - 1174
  • [43] p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    Urist, M
    Tanaka, T
    Poyurovsky, MV
    Prives, C
    GENES & DEVELOPMENT, 2004, 18 (24) : 3041 - 3054
  • [44] Correlation between Molecular Docking and the Stabilizing Interaction of HOMO-LUMO: Spirostans in CHK1 and CHK2, an In Silico Cancer Approach
    Rosales-Lopez, Antonio
    Lopez-Castillo, Guiee N.
    Sandoval-Ramirez, Jesus
    Teran, Joel L.
    Carrasco-Carballo, Alan
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (16)
  • [45] Targeting Chk2 kinase: Molecular interaction maps and therapeutic rationale
    Pommier, Y
    Sordet, O
    Rao, VA
    Zhang, HL
    Kohn, KW
    CURRENT PHARMACEUTICAL DESIGN, 2005, 11 (22) : 2855 - 2872
  • [46] Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy
    M Bartucci
    S Svensson
    P Romania
    R Dattilo
    M Patrizii
    M Signore
    S Navarra
    F Lotti
    M Biffoni
    E Pilozzi
    E Duranti
    S Martinelli
    C Rinaldo
    A Zeuner
    M Maugeri-Saccà
    A Eramo
    R De Maria
    Cell Death & Differentiation, 2012, 19 : 768 - 778
  • [47] Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy
    Bartucci, M.
    Svensson, S.
    Romania, P.
    Dattilo, R.
    Patrizii, M.
    Signore, M.
    Navarra, S.
    Lotti, F.
    Biffoni, M.
    Pilozzi, E.
    Duranti, E.
    Martinelli, S.
    Rinaldo, C.
    Zeuner, A.
    Maugeri-Sacca, M.
    Eramo, A.
    De Maria, R.
    CELL DEATH AND DIFFERENTIATION, 2012, 19 (05): : 768 - 778
  • [48] 下调Chk1和Chk2基因促进射线照射后HeLa细胞凋亡
    高庆蕾
    叶飞
    邢辉谢
    大兴
    卢运萍
    周剑锋
    马丁
    中华肿瘤杂志, 2009, (03)
  • [49] CHK1 targeting as a therapeutic strategy in soft-tissue sarcomas
    Cousin, S.
    Toulmonde, M.
    Rey, C.
    Laroche, A.
    Lucchesi, C.
    Bourdon, A.
    Coindre, J. M.
    Schutzman, J.
    Italiano, A.
    EUROPEAN JOURNAL OF CANCER, 2016, 69 : S6 - S6
  • [50] Check point kinase 1 (Chk1) targeting as a novel therapeutic strategy in small cell lung cancer (SCLC)
    Valliani, Aly A.
    Sen, Triparna
    Masrorpour, Fatehmeh
    Diao, Lixia
    Cardnell, Robert J.
    Wang, Jing
    Glisson, Bonnie S.
    Piwnica-Worms, Helen
    Gibbons, Don L.
    Byers, Lauren A.
    CANCER RESEARCH, 2015, 75
12345