Protrusion-derived vesicles: new subtype of EVs?

被引:8
|
作者
D'Angelo, Gisela [1 ]
Raposo, Graca [1 ]
Nishimura, Tamako [2 ]
Suetsugu, Shiro [2 ]
机构
[1] PSL Res Univ, Inst Curie, UMR144, CNRS, Paris, France
[2] Nara Inst Sci & Technol, Nara, Japan
关键词
D O I
10.1038/s41580-022-00555-x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cellular protrusions are highly dynamic structures that facilitate cell-cell communication and are increasingly recognised for their roles in the shedding of bioactive extracellular vesicles (EVs). The intrinsic and extrinsic mechanisms that govern the shedding of EVs from cellular protrusions and their potential physiological roles are beginning to emerge. This Comment draws attention to cellular protrusions as a source of extracellular vesicles (EVs). These protrusion-derived vesicles expand the repertoire of EVs, impacting current nomenclature and our understanding of EV functions in inter-cellular communication.
引用
收藏
页码:81 / 82
页数:2
相关论文
共 50 条
  • [21] The Methods of Choice for Extracellular Vesicles (EVs) Characterization
    Szatanek, Rafal
    Baj-Krzyworzeka, Monika
    Zimoch, Jakub
    Lekka, Malgorzata
    Siedlar, Maciej
    Baran, Jarek
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (06)
  • [22] Adipogenic RNAs are transferred in osteoblasts via bone marrow adipocytes-derived extracellular vesicles (EVs)
    Martin, Perrine J.
    Haren, Nathalie
    Ghali, Olfa
    Clabaut, Aline
    Chauveau, Christophe
    Hardouin, Pierre
    Broux, Odile
    BMC CELL BIOLOGY, 2015, 16
  • [23] miRNA and mRNA detection in plasma-derived extracellular vesicles (EVs) using the nCounter NanoString platform
    Bracht, Jillian Wilhelmina
    Gimenez-Capitan, Ana
    Huang, Chung-Ying
    Pedraz-Valdunciel, Carlos
    Valarezo, Joselyn
    Warren, Sarah
    Rosell, Rafael
    Molina-Vila, Miguel Angel
    CANCER RESEARCH, 2020, 80 (16)
  • [24] Extracellular vesicles (EVs) derived from osteotropic tumors inhibit osteoblast differentiation and increase osteoclastogenesis and angiogenesis
    Cappariello, Alfredo
    Green, Alice
    George, Christopher
    Shefferd, Kirsty
    Ucci, Argia
    Loftus, Alexander
    Delle Monache, Shnona
    Ponzetti, Marco
    Teti, Anna
    Rucci, Nadia
    Muraca, Maurizio
    JOURNAL OF BONE AND MINERAL RESEARCH, 2019, 34 : 365 - 365
  • [25] COMPARATIVE ANALYSIS OF EXTRACELLULAR VESICLES (EVS) DERIVED FROM ADIPOSE TISSUE- AND BONE MARROW- DERIVED MESENCHYMAL STROMAL CELLS
    Gorgun, Cansu
    Elisabetta, Maria
    Palama, Federica
    Reverberi, Daniele
    Tasso, Roberta
    Gentili, Chiara
    TISSUE ENGINEERING PART A, 2022, 28 : S397 - S397
  • [26] Uterine Fluid (UF)-Derived Extracellular Vesicles (EVs) as a Potential Noninvasive Proxy of Endometrial Transcriptomic Status.
    Giacomini, Elisa
    Scotti, Giulia Maria
    Lazarevic, Dejan
    Simeoni, Fabio
    Molineris, Ivan
    Makieva, Sofia
    Papaleo, Enrico
    Tonon, Giovanni
    Vigano, Paola
    REPRODUCTIVE SCIENCES, 2019, 26 : 104A - 104A
  • [27] Procoagulant Activity of Umbilical Cord-Derived Mesenchymal Stromal Cells' Extracellular Vesicles (MSC-EVs)
    Wright, Adrienne
    Snyder, Orman
    He, Hong
    Christenson, Lane K.
    Fleming, Sherry
    Weiss, Mark L.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (11)
  • [28] Signal amplification strategies in biosensing of extracellular vesicles (EVs)
    Khaksari, Sedighe
    Abnous, Khalil
    Hadizadeh, Farzin
    Ramezani, Mohammad
    Taghdisi, Seyed Mohammad
    Shaegh, Seyed Ali Mousavi
    TALANTA, 2023, 256
  • [29] Biological function of Extracellular Vesicles (EVs): a review of the field
    Mohammadipoor, Arezoo
    Hershfield, Megan R.
    Linsenbardt, Hans R.
    Smith, James
    Mack, James
    Natesan, Shanmugasundaram
    Averitt, Dayna L.
    Stark, Thomas R.
    Sosanya, Natasha M.
    MOLECULAR BIOLOGY REPORTS, 2023, 50 (10) : 8639 - 8651
  • [30] Biology and Role of Extracellular Vesicles (EVs) in the Pathogenesis of Thrombosis
    Zara, Marta
    Guidetti, Gianni Francesco
    Camera, Marina
    Canobbio, Ilaria
    Amadio, Patrizia
    Torti, Mauro
    Tremoli, Elena
    Barbieri, Silvia Stella
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (11)