Indole-Containing Metal Complexes and Their Medicinal Applications

被引：5
|
作者：
Kazemi, Zahra [1 ]
Rudbari, Hadi Amiri [1 ]
Moini, Nakisa [2 ]
Momenbeik, Fariborz [1 ]
Carnamucio, Federica [3 ]
Micale, Nicola [3 ]
机构：
[1] Univ Isfahan, Dept Chem, Esfahan 8174673441, Iran
[2] Alzahra Univ, Fac Phys & Chem, Dept Chem, Tehran 1993893973, Iran
[3] Univ Messina, Dept Chem Biol Pharmaceut & Environm Sci, Viale Ferdinando Stagno Alcontres 31, I-98166 Messina, Italy
来源：
MOLECULES | 2024年 / 29卷 / 02期
关键词：
indole; metal complexes; medicinal applications; biological activity; PROTEIN-BINDING PROPERTIES; SPECTROSCOPIC CHARACTERIZATION; POLYQ AGGREGATION; ENHANCEMENT; HETEROCYCLES; THERAPEUTICS; DERIVATIVES; DISCOVERY; CHAPERONE; SCAFFOLD;
D O I：
10.3390/molecules29020484
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal agents. This review covers some of the latest and most relevant achievements in the biological and pharmacological activity of important indole-containing metal complexes in the area of drug discovery.
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页数：34
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