Indole-Containing Metal Complexes and Their Medicinal Applications

被引：5

作者：

Kazemi, Zahra ^{[1
]}

Rudbari, Hadi Amiri ^{[1
]}

Moini, Nakisa ^{[2
]}

Momenbeik, Fariborz ^{[1
]}

Carnamucio, Federica ^{[3
]}

Micale, Nicola ^{[3
]}

机构：

[1] Univ Isfahan, Dept Chem, Esfahan 8174673441, Iran

[2] Alzahra Univ, Fac Phys & Chem, Dept Chem, Tehran 1993893973, Iran

[3] Univ Messina, Dept Chem Biol Pharmaceut & Environm Sci, Viale Ferdinando Stagno Alcontres 31, I-98166 Messina, Italy

来源：

MOLECULES | 2024年 / 29卷 / 02期

关键词：

indole; metal complexes; medicinal applications; biological activity; PROTEIN-BINDING PROPERTIES; SPECTROSCOPIC CHARACTERIZATION; POLYQ AGGREGATION; ENHANCEMENT; HETEROCYCLES; THERAPEUTICS; DERIVATIVES; DISCOVERY; CHAPERONE; SCAFFOLD;

D O I：

10.3390/molecules29020484

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal agents. This review covers some of the latest and most relevant achievements in the biological and pharmacological activity of important indole-containing metal complexes in the area of drug discovery.

引用

页数：34

共 50 条

[41] Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands
Zhang, XQ
Li, XJ
Allan, GF
Musto, A
Lundeen, SG
Sui, ZH
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (12) : 3233 - 3237
[42] UNUSUAL FORMATION OF NEW INDOLE-CONTAINING HETEROCYCLIC RING-SYSTEMS
BLACK, DS
CHAICHIT, N
GATEHOUSE, BM
MOSS, GI
AUSTRALIAN JOURNAL OF CHEMISTRY, 1987, 40 (12) : 1965 - 1977
[43] DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL INDOLE-CONTAINING SORAFENIB DERIVATIVES
Fan, Sili
Fu, Yihong
Tang, Siyu
Chen, Danping
Li, Zhurui
Li, Chengpeng
Shao, Lihui
Wang, Zhenchao
Ouyang, Guiping
HETEROCYCLES, 2022, 104 (04) : 667 - 688
[44] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy
Luo, Meng-Lan
Huang, Wei
Zhu, Hong-Ping
Peng, Cheng
Zhao, Qian
Han, Bo
BIOMEDICINE & PHARMACOTHERAPY, 2022, 149
[45] ELECTRON ABSORPTION-SPECTRA OF TETRACYCLIC INDOLE-CONTAINING CONDENSED COMPOUNDS
KHOSHTARIYA, TE
ZAITSEV, BE
KOSTITSYN, AB
SHEBAN, GV
STEPANOVA, GP
SUVOROV, NN
IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 1990, 33 (09): : 3 - 6
[46] Synthesis of tetracyclic indole-containing ring systems by intramolecular cycloadditions of azomethine ylides
Coldham, Iain
Dobson, Benjamin C.
Franklin, Andrew I.
Fletcher, Stephen R.
TETRAHEDRON LETTERS, 2007, 48 (05) : 873 - 875
[47] MEDICINAL APPLICATIONS OF INDOLE-DERIVATIVES
SUGDEN, JK
YOLOYE, TO
PHARMACEUTICA ACTA HELVETIAE, 1978, 53 (3-4): : 65 - 92
[48] Synthesis and characterization of indole-containing chromophores for second-order nonlinear optics
Gong, Wei
Li, Qianqian
Li, Zhen
Lu, Changgui
Zhu, Jing
Li, Sueyue
Yang, Junwei
Cui, Yiping
Qin, Jingui
JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (21): : 10241 - 10247
[49] Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase
Lee, Yeon-Ju
Han, Yu-Ri
Park, Wanki
Nam, Seo-Hee
Oh, Ki-Bong
Lee, Hyi-Seung
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (23) : 6882 - 6885
[50] Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids
Shchegravina, Ekaterina S.
Maleev, Alexander A.
Ignatov, Stanislav K.
Gracheva, Iuliia A.
Stein, Andreas
Schmalz, Hans-Guenther
Gavryushin, Andrey E.
Zubareva, Anastasiya A.
Svirshchevskaya, Elena V.
Fedorov, Alexey Yu.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 141 : 51 - 60

← 1 2 3 4 5 →