Flavonoid Diglycosides from Dendrobium officinale Leaves and Their Tyrosinase Inhibitory Activity

被引：1
|
作者：
Chen, Yi-Fang [1 ,2 ,3 ,4 ]
Luo, Ji-Feng [3 ,4 ]
Zhang, Yan-Ni [1 ,2 ]
Wang, Yue-Hu [3 ,4 ]
机构：
[1] Shaanxi Normal Univ, Natl Engn Lab Resource Dev Endangered Crude Drugs, Key Lab Med Resources & Nat Pharmaceut Chem, Minist Educ, Xian 710119, Peoples R China
[2] Shaanxi Normal Univ, Sch Life Sci, Xian 710119, Peoples R China
[3] Chinese Acad Sci, Kunming Inst Bot, Key Lab Econ Plants & Biotechnol, Kunming 650201, Yunnan, Peoples R China
[4] Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Wild Plant Resources, Kunming 650201, Yunnan, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 06期
关键词：
Orchidaceae; Dendrobium officinale; flavonoid diglycosides; C-glycosides; tyrosinase inhibitory activity; GLYCOSIDES;
D O I：
10.1007/s10600-023-04198-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Four flavonoid C-glycosides, including two new diglycosides, dendrodiglycosides A (1) and B (2), along with known isoviolanthin (3) and apigenin 6-C-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-arabinopyranoside (4), were isolated from the leaves of Dendrobium officinale (Orchidaceae). Their structures were elucidated by NMR and MS. Apigenin 6-C-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-arabinopyranoside exhibited an inhibitory effect against tyrosinase with an IC50 value of 146.5 mu g/mL.
引用
收藏
页码：1067 / 1074
页数：8
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