On the role of polyploid giant cells in oncogenesis and tumorigenesis

被引：0
|
作者：
Niculescu, Vladimir F.
机构：
来源：
MEDICAL ONCOLOGY | 2023年 / 40卷 / 08期
关键词：
D O I：
10.1007/s12032-023-02089-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This correspondence is in response to the commentary by Jinsong Liu (https:// doi.org/10.1007/s12032-023-02038-1) to my article "The evolutionary cancer gene network theory versus embryogenic hypotheses" published in Medical Oncology (40:114, 2023). Liu's commentary engages head-on with the evolutionary cancer genome theory and defends his more histopathologically-embryogenically oriented theory of 2020. The dispute revolves, among other things, around the role of polyploid giant MGRS/PGCCs structures in oncogenesis and tumorigenesis.
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