On the role of polyploid giant cells in oncogenesis and tumorigenesis

被引：0
|
作者：
Niculescu, Vladimir F.
机构：
来源：
MEDICAL ONCOLOGY | 2023年 / 40卷 / 08期
关键词：
D O I：
10.1007/s12032-023-02089-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This correspondence is in response to the commentary by Jinsong Liu (https:// doi.org/10.1007/s12032-023-02038-1) to my article "The evolutionary cancer gene network theory versus embryogenic hypotheses" published in Medical Oncology (40:114, 2023). Liu's commentary engages head-on with the evolutionary cancer genome theory and defends his more histopathologically-embryogenically oriented theory of 2020. The dispute revolves, among other things, around the role of polyploid giant MGRS/PGCCs structures in oncogenesis and tumorigenesis.
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Zoledronic acid targets chemo-resistant polyploid giant cancer cells
    Rezvan Adibi
    Shiva Moein
    Yousof Gheisari
    Scientific Reports, 13 (1)
  • [32] JNK and Yorkie drive tumor progression by generating polyploid giant cells in Drosophila
    Bojie Cong
    Shizue Ohsawa
    Tatsushi Igaki
    Oncogene, 2018, 37 : 3088 - 3097
  • [33] Simulated microgravity increases polyploid giant cancer cells and nuclear localization of YAP
    Arun, Raj Pranap
    Sivanesan, Divya
    Patra, Bamadeb
    Varadaraj, Sudha
    Verma, Rama Shanker
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [34] Polyploid giant cancer cells induce growth arrest and cytoskeletal rearrangement in breast cancer cells
    Bharadwaj, D.
    Parekh, A.
    Das, S.
    Jena, B. C.
    Mandal, M.
    NEW BIOTECHNOLOGY, 2018, 44 : S141 - S141
  • [35] Polyploid Giant Cancer Cells Are Frequently Found in the Urine of Prostate Cancer Patients
    Castillo, Laura Nalleli Garrido
    Anract, Julien
    Delongchamps, Nicolas Barry
    Huillard, Olivier
    BenMohamed, Fatima
    Decina, Alessandra
    Lebret, Thierry
    Dachez, Roger
    Paterlini-Brechot, Patrizia
    CANCERS, 2023, 15 (13)
  • [36] Circulating Polyploid Giant Cancer Cells, a Potential Prognostic Marker in Patients with Carcinoma
    Chinen, Ludmilla Thome Domingos
    Torres, Jacqueline Aparecida
    Calsavara, Vinicius Fernando
    Brito, Angelo Borsarelli Carvalho
    Silva, Virgilio Sousa e
    Novello, Roberto Gabriel Santiago
    Fernandes, Thaissa Carvalho
    Decina, Alessandra
    Dachez, Roger
    Paterlini-Brechot, Patrizia
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (18)
  • [37] Molecular cytogenetic characterization of Polyploid Giant Cancer Cells (PGCCs) in cytarabine-resistant AML cells
    Chen, Pei-Yi
    Lin, Yu-Xuan
    Wu, Chia-Ling
    Yen, Jui-Hung
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 1251 - 1252
  • [38] Molecular cytogenetic characterization of Polyploid Giant Cancer Cells (PGCCs) in cytarabine-resistant AML cells
    Lin, Yu Xuan
    Yen, Jui Hung
    Wu, Chia Ling
    Lin, Liang In
    Chen, Pei Yi
    CANCER SCIENCE, 2025, 116 : 1596 - 1596
  • [39] Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells
    Niu, N.
    Mercado-Uribe, I.
    Liu, J.
    ONCOGENE, 2017, 36 (34) : 4887 - 4900
  • [40] Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells
    N Niu
    I Mercado-Uribe
    J Liu
    Oncogene, 2017, 36 : 4887 - 4900
12345