Severe hypocalcemia after denosumab administration in a patient with chronic kidney disease: a case report

被引：0

作者：

Kouroglou, Eleni ^{[1
]}

Tsiama, Vasiliki ^{[1
]}

Dionysopoulou, Sofia ^{[1
]}

Gavriiloglou, Georgios ^{[1
]}

Bora, Margarita ^{[2
]}

Belis, Konstantinos ^{[1
]}

Proikaki, Stella ^{[1
]}

Savvidis, Christos ^{[1
]}

Giannou, Panagiota ^{[2
]}

Petras, Dimitrios ^{[2
]}

机构：

[1] Hippocrat Hosp, Endocrinol & Metab Dept, Athens, Greece

[2] Hippocrat Hosp, Nephrol Dept, Athens, Greece

来源：

JOURNAL OF MUSCULOSKELETAL & NEURONAL INTERACTIONS | 2023年 / 23卷 / 02期

关键词：

Bones; Calcium; Denosumab; Hypocalcemia; BONE-MINERAL DENSITY; INCREASED RISK; HIP; METASTASES; FRACTURES; EFFICACY; SAFETY; LEVEL;

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Patients with altered kidney function are at increased risk of hypocalcemia after denosumab administration. There is however a small number of studies and case reports describing hypocalcemia refractory to treatment. We describe a case of severe hypocalcemia, after the administration of three doses of denosumab, in a young patient with lupus nephritis under corticosteroid coverage and osteopenia. However, more studies are needed in order to extract a safe conclusion about the factors that contribute to the development of severe hypocalcemia in this group of patients.

引用

页码：285 / 289

页数：5

共 50 条

[41] Hypocalcemia after Denosumab in a Pulmonary Hypertension Patient Receiving Epoprostenol
De Muynck, Benedicte
Leys, Mathias
Cuypers, Joke
Vanderschueren, Dirk
Delcroix, Marion
Belge, Catharina
RESPIRATION, 2018, 95 (02) : 139 - 142
[42] Denosumab-induced severe hypocalcemia in a patient with Paget's disease of bone and impaired renal function
Kostine, Marie
Mehsen-Cetre, Nadia
Bannwarth, Bernard
THERAPIE, 2017, 72 (03): : 383 - 385
[43] SEVERE HYPOCALCEMIA ASSOCIATED WITH CHRONIC GLUTETHIMIDE ADDICTION - A CASE-REPORT
OBER, KP
HENNESSY, JF
HELLMAN, RM
AMERICAN JOURNAL OF PSYCHIATRY, 1981, 138 (09): : 1239 - 1240
[44] Interaction between ferric carboxymaltose and denosumab causing severe hypocalcaemia and hypophosphataemia in a patient without chronic kidney disease
Muhandiramge, Jaidyn
Lee, Vivian
Tran, Monica
Ho, Lannie
INTERNAL MEDICINE JOURNAL, 2023, 53 (07) : 1273 - 1276
[45] The Effect of Denosumab on Risk for Emergently Treated Hypocalcemia by Stage of Chronic Kidney Disease: A Target Trial Emulation
Bird, Steven T.
Gelperin, Kate
Smith, Elizabeth R.
Jung, Tae Hyun
Lyu, Hai
Thompson, Aliza
Easley, Olivia
Naik, Kushal B.
Zhao, Yueqin
Kambhampati, Rekha
Wernecke, Michael
Niak, Ali
Zemskova, Marina
Chillarige, Yoganand
Kelman, Jeffrey A.
Graham, David J.
ANNALS OF INTERNAL MEDICINE, 2025, 178 (01) : 29 - +
[46] Denosumab/rosuvastatin interactionAcute kidney injury in an elderly patient: case report
Reactions Weekly, 2013, 1449 (1) : 13 - 13
[47] Electromyographic changes in a patient with hypocalcemia after thyroidectomy: A case report
Min, Hoisik
Lee, Chang Han
TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, 2022, 68 (03): : 422 - 425
[48] DENOSUMAB IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Monov, Simeon
Monova, Daniela
Shumnalieva, Russka
Stambolova, Maria
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2019, 25 : S72 - S73
[49] Denosumab-induced hypocalcemia post bariatric surgery-a severe and protracted course: a case report
Awang, Mohd Hazriq
Hatta, Sharifah Faradila Wan Muhamad
Mohamad, Aimi Fadilah
Ghani, Rohana Abdul
JOURNAL OF MEDICAL CASE REPORTS, 2023, 17 (01)
[50] Severe Hypocalcemia Following a Third Denosumab Injection in a Patient with Moderate Renal Insufficiency
Quang Vutrong Ton
Wttlin, Steven David
ENDOCRINE REVIEWS, 2014, 35 (03)

← 1 2 3 4 5 →