Severe hypocalcemia after denosumab administration in a patient with chronic kidney disease: a case report

被引：0

作者：

Kouroglou, Eleni ^{[1
]}

Tsiama, Vasiliki ^{[1
]}

Dionysopoulou, Sofia ^{[1
]}

Gavriiloglou, Georgios ^{[1
]}

Bora, Margarita ^{[2
]}

Belis, Konstantinos ^{[1
]}

Proikaki, Stella ^{[1
]}

Savvidis, Christos ^{[1
]}

Giannou, Panagiota ^{[2
]}

Petras, Dimitrios ^{[2
]}

机构：

[1] Hippocrat Hosp, Endocrinol & Metab Dept, Athens, Greece

[2] Hippocrat Hosp, Nephrol Dept, Athens, Greece

来源：

JOURNAL OF MUSCULOSKELETAL & NEURONAL INTERACTIONS | 2023年 / 23卷 / 02期

关键词：

Bones; Calcium; Denosumab; Hypocalcemia; BONE-MINERAL DENSITY; INCREASED RISK; HIP; METASTASES; FRACTURES; EFFICACY; SAFETY; LEVEL;

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Patients with altered kidney function are at increased risk of hypocalcemia after denosumab administration. There is however a small number of studies and case reports describing hypocalcemia refractory to treatment. We describe a case of severe hypocalcemia, after the administration of three doses of denosumab, in a young patient with lupus nephritis under corticosteroid coverage and osteopenia. However, more studies are needed in order to extract a safe conclusion about the factors that contribute to the development of severe hypocalcemia in this group of patients.

引用

页码：285 / 289

页数：5

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