A flexible system for tissue-specific gene expression in mice using adeno-associated virus

被引：0
|
作者：
Zengel, James [1 ]
Carette, Jan E. [1 ]
机构：
[1] Stanford Univ, Sch Med, Stanford, CA 94305 USA
来源：
NATURE METHODS | 2023年 / 20卷 / 07期
关键词：
D O I：
10.1038/s41592-023-01897-w
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Cell type-specific transgene expression in mice has broad utility in biomedical research. We developed a versatile system for in vivo transgene delivery using adeno-associated virus (AAV). Efficient and tissue-specific transgene expression is achieved by regulating the expression of the gene encoding the AAV receptor, thereby precisely targeting AAV to the cell type of interest.
引用
收藏
页码：997 / 998
页数：2
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