共 50 条
Treatment of immune-mediated keratitis (IMMK) in dogs with immunosuppressants observed with spectral domain optical coherence tomography (SD-OCT)
被引:0
|作者:
Kim, Hyelin
Jeong, Youngseok
Lee, Eunji
Seo, Kangmoon
Kang, Seonmi
机构:
[1] Seoul Natl Univ, Dept Vet Clin Sci, Coll Vet Med, Seoul 08826, South Korea
[2] Seoul Natl Univ, Res Inst Vet Sci, Seoul 08826, South Korea
基金:
新加坡国家研究基金会;
关键词:
Canine disease;
corneal opacity;
keratopathy;
stromal corneal dystrophy;
tacrolimus;
CORNEAL;
D O I:
10.4142/jvs.23059
中图分类号:
S85 [动物医学(兽医学)];
学科分类号:
0906 ;
摘要:
Two dogs presented with bilateral pattern-forming corneal opacity. Treatment with topical immunosuppressants was initiated after a complete ophthalmic examination. The response to treatment was assessed by analyzing serial images using slit-lamp biomicroscopy and spectral domain optical coherence tomography (SD-OCT). Both dogs responded to topical immunosuppressants; however, the lesions recurred once the treatment was abated or withdrawn. The most effective immunosuppressant in both dogs was 0.03% tacrolimus ointment. Early and continuous treatment with topical immunosuppressants may be necessary to improve corneal clarity and prevent scarring. SD- OCT could provide useful structural information regarding presumed immune-mediated keratitis and aid in monitoring treatment response.
引用
收藏
页数:7
相关论文