Treatment of immune-mediated keratitis (IMMK) in dogs with immunosuppressants observed with spectral domain optical coherence tomography (SD-OCT)

被引:0
|
作者
Kim, Hyelin
Jeong, Youngseok
Lee, Eunji
Seo, Kangmoon
Kang, Seonmi
机构
[1] Seoul Natl Univ, Dept Vet Clin Sci, Coll Vet Med, Seoul 08826, South Korea
[2] Seoul Natl Univ, Res Inst Vet Sci, Seoul 08826, South Korea
基金
新加坡国家研究基金会;
关键词
Canine disease; corneal opacity; keratopathy; stromal corneal dystrophy; tacrolimus; CORNEAL;
D O I
10.4142/jvs.23059
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Two dogs presented with bilateral pattern-forming corneal opacity. Treatment with topical immunosuppressants was initiated after a complete ophthalmic examination. The response to treatment was assessed by analyzing serial images using slit-lamp biomicroscopy and spectral domain optical coherence tomography (SD-OCT). Both dogs responded to topical immunosuppressants; however, the lesions recurred once the treatment was abated or withdrawn. The most effective immunosuppressant in both dogs was 0.03% tacrolimus ointment. Early and continuous treatment with topical immunosuppressants may be necessary to improve corneal clarity and prevent scarring. SD- OCT could provide useful structural information regarding presumed immune-mediated keratitis and aid in monitoring treatment response.
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页数:7
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