A MULTIPLEXED BIOAFFINITY BIOSENSING PATCH FOR POINT-OF-CARE CHRONIC ULCER MONITORING

被引：0
|
作者：
Sharifuzzaman, Md [1 ]
Kim, Dongkyun [1 ]
Reza, Md Selim [1 ]
Jeong, SeongHoon [1 ]
Song, Hye Su [1 ]
Abu Zahed, Md [1 ]
Park, J. Y. [1 ]
机构：
[1] Kwangwoon Univ, Dept Elect Engn, Seoul, South Korea
来源：
2023 IEEE 36TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, MEMS | 2023年
关键词：
Multiplexed biosensing patch; Microfluidic wound exudate collector; Antifouling coating; Chronic ulcer monitoring;
D O I：
10.1109/MEMS49605.2023.10052565
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
This paper reports a flexible multiplexed biosensing patch integrated with a bioinspired microfluidic wound exudate collector for dynamic assessment of the wound's inflammatory milieu and infection status at the point-of-care. The immunosensors platform was functionalized by integrating a MXene (Ti3C2Tx)-based antifouling nanocomposite that resists biofouling while preserving electroconductivity. As a proof of concept, we successfully demonstrated three panels profiling including interleukin-6 (linear range 0-40 ng mL(-1)), temperature (sensitivity 0.08% degrees C-1 in the physiological range of 25- 50 degrees C), and pH (sensitivity of -60 mV pH(-1) in the wound relevant pH range of 3-9) in human serum.
引用
收藏
页码：197 / 200
页数：4
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