A MULTIPLEXED BIOAFFINITY BIOSENSING PATCH FOR POINT-OF-CARE CHRONIC ULCER MONITORING

被引：0

作者：

Sharifuzzaman, Md ^{[1
]}

Kim, Dongkyun ^{[1
]}

Reza, Md Selim ^{[1
]}

Jeong, SeongHoon ^{[1
]}

Song, Hye Su ^{[1
]}

Abu Zahed, Md ^{[1
]}

Park, J. Y. ^{[1
]}

机构：

[1] Kwangwoon Univ, Dept Elect Engn, Seoul, South Korea

来源：

2023 IEEE 36TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, MEMS | 2023年

关键词：

Multiplexed biosensing patch; Microfluidic wound exudate collector; Antifouling coating; Chronic ulcer monitoring;

D O I：

10.1109/MEMS49605.2023.10052565

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper reports a flexible multiplexed biosensing patch integrated with a bioinspired microfluidic wound exudate collector for dynamic assessment of the wound's inflammatory milieu and infection status at the point-of-care. The immunosensors platform was functionalized by integrating a MXene (Ti3C2Tx)-based antifouling nanocomposite that resists biofouling while preserving electroconductivity. As a proof of concept, we successfully demonstrated three panels profiling including interleukin-6 (linear range 0-40 ng mL(-1)), temperature (sensitivity 0.08% degrees C-1 in the physiological range of 25- 50 degrees C), and pH (sensitivity of -60 mV pH(-1) in the wound relevant pH range of 3-9) in human serum.

引用

页码：197 / 200

页数：4

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