Validation of genotype array analysis for the assessment of homologous recombination deficiency (HRD) in epithelial ovarian cancer

被引：0
|
作者：
Schnaiter, Simon [1 ]
Schamschula, Esther [1 ]
Zschocke, Johannes [1 ]
Fiegl, Heidi [2 ]
Reimer, Daniel U. [2 ]
Zeimet, Alain [2 ]
Wimmer, Katharina [1 ]
机构：
[1] Med Univ Innsbruck, Inst Human Genet, Innsbruck, Austria
[2] Med Univ Innsbruck, Dept Obstet & Gynecol, Innsbruck, Austria
来源：
EUROPEAN JOURNAL OF HUMAN GENETICS | 2023年 / 31卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P13.091.A
引用
收藏
页码：555 / 556
页数：2
相关论文
共 50 条
  • [41] Development of model for identifying homologous recombination deficiency (HRD) status of ovarian cancer with deep learning on whole slide images
    Zhang, Ke
    Qiu, Youhui
    Feng, Songwei
    Yin, Han
    Liu, Qi
    Zhu, Yuxin
    Cui, Haoyu
    Wei, Xiaoying
    Wang, Guoqing
    Wang, Xiangxue
    Shen, Yang
    JOURNAL OF TRANSLATIONAL MEDICINE, 2025, 23 (01)
  • [42] Homologous recombination deficiency (HRD) testing landscape: clinical applications and technical validation for routine diagnostics
    Witz, Andrea
    Dardare, Julie
    Betz, Margaux
    Michel, Cassandra
    Husson, Marie
    Gilson, Pauline
    Merlin, Jean-Louis
    Harle, Alexandre
    BIOMARKER RESEARCH, 2025, 13 (01)
  • [43] Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer
    Rodrigues, Angelica Nogueira
    Souto, Andreza Karine de Barros Almeida
    de Andrade, Diocesio Alves Pinto
    Gomes, Larissa Mueller
    Koide, Sandra Satie
    Silva, Renata de Godoy
    de Souza, Bruno Batista
    Massaro, Juliana Doblas
    de Melo, Andreia Cristina
    Borges, Andrea Morais
    Giro, Camila
    de Andrade, Carlos Augusto Vasconcelos
    da Costa, Cesar Martins
    Gimenes, Daniel Luiz
    de Mello, Eduardo Caminha Bandeira
    de Oliveira, Fernanda Cesar
    Lima, Frederico Mueller de Toledo
    Lopes, Gabriel Lima
    Bretas, Gustavo de Oliveira
    Jacob, Gustavo Guerra
    da Costa e Silva, Herika Lucia
    Notaro, Juliana Ferrari
    Alves, Lara Ladislau
    Moitinho, Marcos Veloso
    da Silva, Mirian Cristina
    Abramoff, Roberto
    Rauber, Thais Amaral da Cunha
    Dienstmann, Rodrigo
    Koyama, Fernanda Christtanini
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2025, 12
  • [44] Breast cancer whole genomes link homologous recombination deficiency (HRD) with therapeutic outcomes
    Zhao, Eric Y.
    Shen, Yaoqing
    Pleasance, Erin
    Kasaian, Katayoon
    Jones, Martin R.
    Ch'ng, Carolyn
    Reisle, Caralyn
    Eirew, Peter
    Mungall, Karen
    Thiessen, Nina
    Ma, Yussanne
    Fok, Alexandra
    Mungall, Andrew J.
    Zhao, Yongjun
    Moore, Richard
    Villa, Diego
    Shenkier, Tamara
    Lohrisch, Caroline
    Chia, Stephen
    Yip, Stephen
    Gelmon, Karen
    Lim, Howard
    Sun, Sophie
    Schrader, Kasmintan A.
    Young, Sean
    Karsan, Aly
    Roscoe, Robyn
    Laskin, Janessa
    Marra, Marco A.
    Jones, Steven J.
    CANCER RESEARCH, 2017, 77
  • [45] Characterization of mutational signatures of homologous recombination deficiency (HRD) in Chinese breast cancer.
    Liu, Xiao
    Li, Mingwei
    Lou, Feng
    Cao, Shanbo
    Wang, Huina
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [46] Stochasticity in threshold of homologous recombination deficiency (HRD) score.
    Xu, Bai
    Xu, Bai
    Kai, Zhentian
    Thi, Phuong Anh Nguyen
    Xia, Chaoran
    Shi, Weiwei
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E17561 - E17561
  • [47] Homologous recombination deficiency testing in Vietnamese patients with ovarian cancer
    Tran, N. H.
    Nguyen, P.
    Nguyen, T. A.
    Tu, L.
    ANNALS OF ONCOLOGY, 2024, 35
  • [48] Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer
    Konstantinopoulos, Panagiotis A.
    Ceccaldi, Raphael
    Shapiro, Geoffrey I.
    D'Andrea, Alan D.
    CANCER DISCOVERY, 2015, 5 (11) : 1137 - 1154
  • [49] Genomic characteristics of homologous recombination deficiency in ovarian cancer.
    Ma, Xiaoxue
    Li, Mingwei
    Lou, Feng
    Cao, Shanbo
    Wang, Huina
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E17575 - E17575
  • [50] Streamline of the gene line: Implementation of reflex homologous recombination deficiency (HRD) tumor testing in newly diagnosed ovarian cancer patients
    Byrne, Maureen
    Mckenna, Danielle
    Schumacher, Ryan
    Shah, Payal
    Mastroyannis, Spyridon Alexandros
    Lodise, Amy
    Oliver, Sirithepphavanh
    Schwartz, Lauren
    Martin, Lainie
    Domchek, Susan
    Haggerty, Ashley
    GYNECOLOGIC ONCOLOGY, 2022, 166 : S287 - S288
12345