Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia

被引：7

作者：

Le, Quy ^{[1
]}

Tang, Thao ^{[1
]}

Leonti, Amanda ^{[1
]}

Castro, Sommer ^{[1
]}

McKay, Cyd Nourigat ^{[1
]}

Perkins, LaKeisha ^{[1
]}

Pardo, Laura ^{[2
]}

Kirkey, Danielle ^{[1
]}

Hylkema, Tiffany ^{[1
]}

Call, Lindsey ^{[1
]}

Manselle, Makia ^{[1
]}

Abrahams, Cristina ^{[3
]}

Bedard, Kristin ^{[3
]}

Molina, Arturo ^{[3
]}

Brodersen, Lisa Eidenshinck ^{[2
]}

Loken, Michael R. ^{[2
]}

Tarlock, Katherine ^{[1
,5
]}

Meshinchi, Soheil ^{[1
,4
,5
]}

Loeb, Keith R. ^{[1
,6
,7
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Clin Res Div, Seattle, WA USA

[2] Hematologics Inc, Seattle, WA USA

[3] Sutro Biopharma, South San Francisco, CA USA

[4] Univ Washington, Dept Pediat, Seattle, WA USA

[5] Childrens Oncol Grp, Monrovia, CA USA

[6] Univ Washington, Dept Lab Med & Pathol, Seattle, WA USA

[7] Fred Hutch Canc Ctr, 1100 Fairview Ave N, Seattle, WA 98109 USA

来源：

BLOOD ADVANCES | 2023年 / 7卷 / 09期

关键词：

INVARIANT CHAIN; PROLIFERATION; SURVIVAL;

D O I：

10.1182/bloodadvances.2022008303

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1666 / 1670

页数：5

共 50 条

[1] Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL
Le, Quy
Leonti, Amanda R.
Tang, Thao T.
Castro, Sommer
Nourigat-Mckay, Cynthia
Perkins, LaKeisha
Ries, Rhonda E.
Smith, Jenny L.
Hylkema, Tiffany A.
Pardo, Laura
Abrahams, Cristina
Bedard, Kristin
Molina, Arturo
Brodersen, Lisa Eidenschink
Loken, Michael R.
Meshinchi, Soheil
BLOOD, 2021, 138
[2] TARGETING CD74 IN MULTIPLE MYELOMA WITH A NOVEL ANTIBODY DRUG CONJUGATE, STRO-001
Embry, M.
Li, X.
DeAlmeida, V.
Abrahams, C.
Yu, A.
Krimm, S.
Krueger, S.
Matheny, S.
Kline, T.
Yam, A.
Stafford, R.
Hallam, T.
Lupher, M.
Molina, A.
HAEMATOLOGICA, 2017, 102 : 106 - 106
[3] Characterization and preclinical development of STRO-001, a novel CD74-targeting antibody-drug conjugate (ADC) for the treatment of B-cell malignancies
Abrahams, Cristina
Li, Xiaofan
DeAlmeida, Venita
Embry, Millicent
Yu, Abigail
Krim, Stellanie
Hoffmann, Heidi
Zawada, James
Bruhns, Maureen
Matheny, Shannon
Bussell, Stuart
Kline, Toni
Yam, Alice
Stafford, Ryan
Hallam, Trevor
Lupher, Mark
Molina, Arturo
CANCER RESEARCH, 2017, 77
[4] CD74 Is Expressed in Relapsed and Refractory Multiple Myeloma and Can be Targeted with a Novel Anti-CD74 Antibody Drug Conjugate, STRO-001
Embry, Millicent
Li, Xiaofan
Yu, Abigail
Abrahams, Cristina
Greenland, Nancy Y.
Wen, Kwun Wah
Jones, Chris
DeAlmeida, Venita
Krimm, Stellanie
Krueger, Sarah
Matheny, Shannon
Kline, Toni
Yam, Alice
Stafford, Ryan
Wiita, Arun P.
Hallam, Trevor
Lupher, Mark
Molina, Arturo
BLOOD, 2017, 130
[5] Nonclinical safety evaluation of STRO-001, a site-specific anti-CD74 antibody-drug conjugate for the potential treatment of B-cell malignancies
Solis, Willy
De Almeida, Venita
Yu, Abigail
Bruhns, Maureen
Zawada, James
Galan, Adam
Matheny, Shannon
Molina, Arturo
Hallam, Trevor
Lupher, Mark
CANCER RESEARCH, 2018, 78 (13)
[6] STRO-001, A NOVEL ANTI-CD74 ANTIBODY DRUG CONJUGATE (ADC) FOR TREATMENT OF B-CELL NON-HODGKIN'S LYMPHOMA (NHL)
Yu, A.
Abrahams, C.
Embry, M.
Li, X.
DeAlmeida, V.
Lee, J.
Matheny, S.
Kline, T.
Yam, A.
Stafford, R.
Hallam, T.
Lupher, M.
Molina, A.
HAEMATOLOGICA, 2017, 102 : 564 - 564
[7] High Frequency of CD74 Expression in B-Cell Non-Hodgkin's Lymphoma (NHL) and Targeting with STRO-001, a Novel Anti-CD74 Antibody Drug Conjugate (ADC) with Potent I n Vitro Cytotoxicty and In Vivo Anti-Tumor Activity
Yu, Abigail
Abrahams, Cristina
Embry, Millicent
Li, Xiaofan
Zhao, Shuchun
Henningsen, Robert
DeAlmeida, Venita
Matheny, Shannon
Kline, Toni
Yam, Alice
Stafford, Ryan
Natkunam, Yasodha
Hallam, Trevor
Lupher, Mark
Molina, Arturo
BLOOD, 2017, 130
[8] Preclinical development of a novel antibody-drug conjugate targeting "cold" tumors
Kaplan, Angelo
Attanasio, Nickolas
Do, To Uyen T.
Swaminathan, Sudha
Bisht, Arnima
Lou, San Lin
Allen, Jason
Boyd, Robert
Ackroyd, James E.
Feldman, Gleb
Rohlff, Christian
Dusek, Rachel L.
CANCER RESEARCH, 2018, 78 (13)
[9] Preclinical evaluation of a novel antibody-drug conjugate targeting DR5 for lymphoblastic leukemia therapy
Zhang, Shuyong
Zhou, Dongdong
Zheng, Chao
Xiong, Peng
Zhu, Wan
Zheng, Dexian
MOLECULAR THERAPY-ONCOLYTICS, 2021, 21 : 329 - 339
[10] A Phase I open-label, safety, pharmacokinetic, and preliminary efficacy study of STRO-001, an anti-CD74 antibody drug conjugate, in patients with advanced B-cell malignancies
Shah, Nirav N.
Krishnan, Amrita Y.
Shah, Nina D.
Burke, John M.
Melear, Jason M.
Spira, Alexander I.
Kaufman, Jonathan L.
Cohen, Jonathon B.
Niesvizky, Ruben
Popplewell, Leslie L.
Chhabra, Saurabh
Sharman, Jeff P.
Martin, Thomas G.
Matheny, Shannon L.
Leonard, John P.
Molina, Arturo
CANCER RESEARCH, 2019, 79 (13)

← 1 2 3 4 5 →