β-Galactosidase-instructed intracellular nanofiber formation enhances tumor micro-PET imaging

被引：0
|
作者：
Wang, Meimei [1 ]
Yu, Kangxia [1 ]
Zhu, Dandan [1 ]
Zou, Pei [2 ]
Chen, Peiyao [3 ]
Wang, Hongyong [2 ]
Liu, Yaling [2 ]
Xie, Minhao [1 ,2 ]
机构：
[1] Nanjing Med Univ, Sch Pharm, Nanjing 211166, Peoples R China
[2] Jiangsu Inst Nucl Med, NHC Key Lab Nucl Med, Jiangsu Key Lab Mol Nucl Med, Wuxi 214063, Peoples R China
[3] Hubei Univ Technol, Natl Ctr Cellular Regulat & Mol Pharmaceut 111, Sch Food & Biol Engn, Key Lab Fermentat Engn, Wuhan 430068, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2023年 / 47卷 / 24期
关键词：
D O I：
10.1039/d3nj01967e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Enzyme-instructed self-assembly is a key approach to prepare well-controlled nanostructures for clinical development. Herein, we report a novel probe, [Ga-68]Nap-1G which self-assembles into nanofibers under the hydrolysis of beta-galactosidase. We demonstrate that its high accumulation enhances micro-PET imaging of tumors.
引用
收藏
页码：11376 / 11379
页数：4
相关论文
共 50 条
  • [41] Effects of fluoxetine on the rat brain in the forced swimming test: A [F-18]FDG micro-PET imaging study
    Jang, Dong-Pyo
    Lee, So-Hee
    Park, Chan-Woong
    Lee, Sang-Yoon
    Kim, Young-Bo
    Cho, Zang-Hee
    NEUROSCIENCE LETTERS, 2009, 451 (01) : 60 - 64
  • [42] Imaging of brain TSPO expression in a mouse model of stroke with [18F]DPA-714 and micro-PET
    Vicidomini, C.
    Vinciguerra, A.
    Greco, A.
    Panico, M. R.
    Gargiulo, S.
    Gramanzini, M.
    Coda, A. R. D.
    Pignataro, G.
    Quarantelli, M.
    Tavitian, B.
    Dolle, F.
    Brunetti, A.
    Salvatore, M.
    Annunziato, L.
    Pappata, S.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 : S450 - S450
  • [43] Simultaneous micro-PET imaging of F-18 and I-124 with correction for triple-random coincidences
    Moore, Stephen C.
    Krishnamoorthy, Srilalan
    Blankemeyer, Eric
    Carlin, Sean D.
    Karp, Joel S.
    Metzler, Scott D.
    15TH INTERNATIONAL MEETING ON FULLY THREE-DIMENSIONAL IMAGE RECONSTRUCTION IN RADIOLOGY AND NUCLEAR MEDICINE, 2019, 11072
  • [44] Micro-PET Imaging of αvβ3-Integrin Expression with 18F-Labeled Dimeric RGD Peptide
    Chen, Xiaoyuan
    Tohme, Michel
    Park, Ryan
    Hou, Yingping
    Bading, James R.
    Conti, Peter S.
    MOLECULAR IMAGING, 2004, 3 (02) : 96 - 104
  • [45] 2-[18F]Fludarabine, a Novel Positron Emission Tomography (PET) Tracer for Imaging Lymphoma: a Micro-PET Study in Murine Models
    Martine Dhilly
    Stéphane Guillouet
    Delphine patin
    Fabien Fillesoye
    Ahmed Abbas
    Fabienne Gourand
    Olivier Tirel
    Françoise Galateau
    Eric T. MacKenzie
    Charles Dumontet
    Michel Leporrier
    Louisa Barré
    Molecular Imaging and Biology, 2014, 16 : 118 - 126
  • [46] 2-[18F]Fludarabine, a Novel Positron Emission Tomography (PET) Tracer for Imaging Lymphoma: a Micro-PET Study in Murine Models
    Dhilly, Martine
    Guillouet, Stephane
    Patin, Delphine
    Fillesoye, Fabien
    Abbas, Ahmed
    Gourand, Fabienne
    Tirel, Olivier
    Galateau, Francoise
    MacKenzie, Eric T.
    Dumontet, Charles
    Leporrier, Michel
    Barre, Louisa
    MOLECULAR IMAGING AND BIOLOGY, 2014, 16 (01) : 118 - 126
  • [47] Casp3/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis
    Yuan, Yue
    Ding, Zhanling
    Qian, Junchao
    Zhang, Jia
    Xu, Jinyong
    Dong, Xuejiao
    Han, Tao
    Ge, Shuchao
    Luo, Yufeng
    Wang, Yuwei
    Zhong, Kai
    Liang, Gaolin
    NANO LETTERS, 2016, 16 (04) : 2686 - 2691
  • [48] High yield and high specific activity synthesis of [18F] fallypride in a batch microfluidic reactor for micro-PET imaging
    Javed, Muhammad Rashed
    Chen, Supin
    Lei, Jack
    Collins, Jeffrey
    Sergeev, Maxim
    Kim, Hee-Kwon
    Kim, Chang-Jin
    van Dam, R. Michael
    Keng, Pei Yuin
    CHEMICAL COMMUNICATIONS, 2014, 50 (10) : 1192 - 1194
  • [49] Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
    Liu, Qing
    Tan, Kel Vin
    Chang, Hing-Chiu
    Khong, Pek-Lan
    Hui, Xiaoyan
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2021, (173):
  • [50] CT-guided Deep Learning Denoising of Low-Dose Micro-PET for Intraoperative Breast Cancer Specimen Imaging
    Balot, E.
    Maris, L.
    Muller, F. M.
    Keereman, V.
    Vandenberghe, S.
    Vanhove, C.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 : S779 - S780
12345