Impact of MYC and BCL2 Double Expression on Outcomes in Primary CNS Lymphoma: A UK Multicenter Analysis

被引：0
|
作者：
Poynton, Edward [1 ,2 ]
Chernucha, Emily [3 ]
Day, James [2 ]
Prodger, Catherine [4 ]
Hopkins, David [5 ]
Rakesh, Pallav [5 ,6 ]
O'Neill, Tess [7 ]
Thakrar, Nisha [2 ]
Akarca, Ayse [8 ]
Jamal, Esraa [1 ]
Ali, Ayesha [9 ]
Kirkwood, Amy A. [10 ]
Pomplun, Sabine [8 ]
Marafioti, Teresa [8 ]
Calaminici, Maria
Greaves, Paul [11 ]
Chaganti, Sridhar [6 ]
Mckay, Pam
Smith, Jeffery [12 ]
Eyre, Toby A.
Martinez-Calle, Nicolas [3 ]
Cwynarski, Kate [2 ]
Fox, Christopher P. [13 ]
Okosun, Jessica
机构：
[1] Queen Mary Univ London, Barts Canc Inst, Ctr Haematooncol, London, England
[2] Univ Coll London Hosp, Dept Clin Haematol, London, England
[3] Nottingham Univ Hosp NHS Trust, Nottingham, England
[4] Oxford Univ Hosp NHS Fdn Trust, Churchill Canc Ctr, Oxford, England
[5] Beatson West Scotland Canc Ctr, Glasgow, Lanark, Scotland
[6] Univ Hosp Birmingham NHS Fdn Trust, Ctr Clin Haematol, Birmingham, W Midlands, England
[7] Barts Hlth NHS Trust, St Bartholomews Hosp, Dept Haemato Oncol, London, England
[8] Univ Coll London Hosp, Dept Histopathol, London, England
[9] Univ Birmingham, Canc Res UK Clin Trials Unit, Birmingham, W Midlands, England
[10] UCL, Canc Res UK, London, England
[11] Barking Havering & Redbridge Univ Hosp NHS Trust, Dept Haematol, London, England
[12] Liverpool Univ Hosp, Clatterbridge Canc Ctr, Liverpool, Merseyside, England
[13] Univ Nottingham, Sch Med, Nottingham, England
来源：
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2023年 / 23卷
关键词：
PCNSL; primary CNS Lymphoma; double expressor; MYC; BCL2;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
ABCL-184
引用
收藏
页码：S423 / S424
页数：2
相关论文
共 50 条
  • [21] Prognostic Significance of Double Expression of C-MYC and BCL2 in Diffuse Large B Cell Lymphoma
    Rashed, Hayam
    Abdelrahman, Aziza Elsayed
    Ismail, Eman
    Obaya, Ahmed
    Abdelhamid, Mohamed
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2017, 17 : S360 - S360
  • [22] Primary Cutaneous Diffuse Large B-Cell Lymphoma With a MYC-IGH Rearrangement and Gain of BCL2: Expanding the Spectrum of MYC/BCL2 Double-Hit Lymphomas
    Testo, Natalia
    Olson, Luke C.
    Subramaniyam, Shivakumar
    Hanson, Ty
    Magro, Cynthia M.
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2016, 38 (10) : 769 - 774
  • [23] MYC, BCL2, and BCL6 expression as prognostic indicators in primary central nervous system lymphoma: A systematic review and meta-analysis
    Ge, Le
    Lu, Shan
    Xu, Lixia
    Yan, Hua
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2021, 208
  • [24] BCL2 inhibition in double hit lymphoma
    Anderson, Mary Ann
    Huang, David C. S.
    Roberts, Andrew W.
    LEUKEMIA & LYMPHOMA, 2015, 56 (07) : 1928 - 1929
  • [25] Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma
    Li, Shaoying
    Saksena, Annapurna
    Desai, Parth
    Xu, Jie
    Zuo, Zhuang
    Lin, Pei
    Tang, Guilin
    Yin, C. Cameron
    Seegmiller, Adam
    Jorgensen, Jeffrey L.
    Miranda, Roberto N.
    Reddy, Nishitha M.
    Bueso-Ramos, Carlos
    Medeiros, L. Jeffrey
    ONCOTARGET, 2016, 7 (25) : 38122 - 38132
  • [26] Prognostic impact of diffuse large B-cell lymphoma with extra copies of MYC, BCL2 and/or BCL6: comparison with double/triple hit lymphoma and double expressor lymphoma
    Huang, Sixia
    Nong, Lin
    Wang, Wei
    Liang, Li
    Zheng, Yalin
    Liu, Jumei
    Li, Dong
    Li, Xin
    Zhang, Bo
    Li, Ting
    DIAGNOSTIC PATHOLOGY, 2019, 14 (1)
  • [27] Prognostic impact of diffuse large B-cell lymphoma with extra copies of MYC, BCL2 and/or BCL6: comparison with double/triple hit lymphoma and double expressor lymphoma
    Sixia Huang
    Lin Nong
    Wei Wang
    Li Liang
    Yalin Zheng
    Jumei Liu
    Dong Li
    Xin Li
    Bo Zhang
    Ting Li
    Diagnostic Pathology, 14
  • [28] Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors
    Weiping Li
    Shiv K. Gupta
    Weiguo Han
    Ryan A. Kundson
    Sara Nelson
    Darlene Knutson
    Patricia T. Greipp
    Sherine F. Elsawa
    Eduardo M. Sotomayor
    Mamta Gupta
    Journal of Hematology & Oncology, 12
  • [29] Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors
    Li, Weiping
    Gupta, Shiv K.
    Han, Weiguo
    Kundson, Ryan A.
    Nelson, Sara
    Knutson, Darlene
    Greipp, Patricia T.
    Elsawa, Sherine F.
    Sotomayor, Eduardo M.
    Gupta, Mamta
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 12 (1)
  • [30] MYC overexpression but not MYC/BCL2 double expression predicts survival in bulky mass diffuse large B-cell lymphoma patients
    Wang, Yanjie
    Liu, Donglin
    Zhang, Xudong
    Zhang, Mingzhi
    Li, Shenglei
    Feng, Xiaoyan
    Dong, Meng
    Ma, Shanshan
    Qian, Siyu
    Wang, Zeyuan
    Zhang, Yue
    Wang, Pengyuan
    Mei, Shuhao
    Chen, Qingjiang
    CANCER MEDICINE, 2023, 12 (18): : 18568 - 18577
12345