Revealing the elevation of Zn2+ in the brain of depressed mice by a ratiometric fluorescent probe with dual near-infrared emissions

被引：10

作者：

Jin, Haobin ^{[1
]}

Ju, Can ^{[1
]}

Duan, Chenxu ^{[1
]}

Zhang, Ningwen ^{[1
]}

Cao, Yongyong ^{[1
]}

Xia, Qineng ^{[1
]}

Zhou, Jin ^{[2
]}

Gao, Shumei ^{[1
]}

Wang, Yangang ^{[1
]}

Huang, Hong ^{[1
]}

机构：

[1] Jiaxing Univ, Coll Biol Chem Sci & Engn, Jiaxing 314001, Peoples R China

[2] Weifang Med Univ, Sch Pharm, Weifang 261053, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 09期

关键词：

ZINC;

D O I：

10.1039/d3cc05529a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mitochondria-targeted ratiometric fluorescent probe (Mito-Zn) was first designed and synthesized with dual emissions both located in the near-infrared region, for Zn2+ detection with high sensitivity and selectivity. By using the developed Mito-Zn, a high level of Zn2+ in the depressed mouse brain was discovered for the first time.

引用

页码：1100 / 1103

页数：5

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