In vivo ratiometric tracking of endogenous β-galactosidase activity using an activatable near-infrared fluorescent probe

被引：50

作者：

Shi, Limin ^{[1
]}

Yan, Chenxu ^{[1
]}

Ma, Yiyu ^{[1
]}

Wang, Ting ^{[1
]}

Guo, Zhiqian ^{[1
]}

Zhu, Wei-Hong ^{[1
]}

机构：

[1] East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Funct Mat Chem, Inst Fine Chem,Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 82期

基金：

中国博士后科学基金;

关键词：

STRATEGY;

D O I：

10.1039/c9cc06869d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we developed a dual-channel and light-up near-infrared fluorescent probe for ratiometric sensing of beta-galactosidase (beta-gal) activity. The well-designed probe, which shows ratiometric optical response with a significant red-shift (from 575 nm to 730 nm), was successfully applied to detect endogenous beta-gal activity in SKOV-3 cells and tumor-bearing mice.

引用

页码：12308 / 12311

页数：4

共 50 条

[1] An activatable ratiometric near-infrared fluorescent probe for hydrogen sulfide imaging in vivo
Luyan Wu
Wenhui Zeng
Liandong Feng
Yuxuan Hu
Yidan Sun
Yingxiao Yan
HongYuan Chen
Deju Ye
Science China(Chemistry) , 2020, (05) : 741 - 750
[2] An activatable ratiometric near-infrared fluorescent probe for hydrogen sulfide imaging in vivo
Wu, Luyan
Zeng, Wenhui
Feng, Liandong
Hu, Yuxuan
Sun, Yidan
Yan, Yingxiao
Chen, Hong-Yuan
Ye, Deju
SCIENCE CHINA-CHEMISTRY, 2020, 63 (05) : 741 - 750
[3] An activatable ratiometric near-infrared fluorescent probe for hydrogen sulfide imaging in vivo
Luyan Wu
Wenhui Zeng
Liandong Feng
Yuxuan Hu
Yidan Sun
Yingxiao Yan
Hong-Yuan Chen
Deju Ye
Science China Chemistry, 2020, 63 (05) : 741 - 750
[4] An activatable ratiometric near-infrared fluorescent probe for hydrogen sulfide imaging in vivo
Luyan Wu
Wenhui Zeng
Liandong Feng
Yuxuan Hu
Yidan Sun
Yingxiao Yan
Hong-Yuan Chen
Deju Ye
Science China Chemistry, 2020, 63 : 741 - 750
[5] An activatable near-infrared fluorescent probe for tracking nitroxyl in vitro and in vivo
Zhou, Zhe
Xia, Xiaofeng
Li, Zheng
Zhou, Tianshuo
Wang, Erfei
Ma, Chao
Lu, Cuifen
Nie, Junqi
Yang, Guichun
Wang, Juan
Fan, Guorun
Ren, Jun
Wang, Feiyi
DYES AND PIGMENTS, 2023, 209
[6] Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe
Gu, Kaizhi
Xu, Yisheng
Li, Hui
Guo, Zhiqian
Zhu, Shaojia
Zhu, Shiqin
Shi, Ping
James, Tony D.
Tian, He
Zhu, Wei-Hong
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (16) : 5334 - 5340
[7] In vivo imaging β-galactosidase activity using a near-infrared dual-channel fluorescent probe
Gu, Kaizhi
Guo, Zhiqian
Tian, He
Zhu, Weihong
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 12 (02) : 514 - 514
[8] A near-infrared fluorescent probe for the ratiometric detection and living cell imaging of β-galactosidase
Xueyan Zhang
Xiangzhu Chen
Yuanyuan Zhang
Kaizheng Liu
Hongjing Shen
En Zheng
Xiaoqian Huang
Shicong Hou
Xiaodong Ma
Analytical and Bioanalytical Chemistry, 2019, 411 : 7957 - 7966
[9] A near-infrared fluorescent probe for the ratiometric detection and living cell imaging of β-galactosidase
Zhang, Xueyan
Chen, Xiangzhu
Zhang, Yuanyuan
Liu, Kaizheng
Shen, Hongjing
Zheng, En
Huang, Xiaoqian
Hou, Shicong
Ma, Xiaodong
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 411 (30) : 7957 - 7966
[10] Rational design of near-infrared ratiometric fluorescent probes for real-time tracking of β-galactosidase in vivo
Chen, Shijun
Liu, Mengyao
Zi, Yunjiang
He, Junyi
Wang, Lin
Wu, Yuanyuan
Hou, Shicong
Wu, Wenxue
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2023, 285

← 1 2 3 4 5 →