Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position

被引:10
|
作者
Li, Luohao [1 ]
Zheng, Huiqin [1 ]
Guo, Feixiang [1 ]
Fang, Zehui [2 ]
Sun, Qianqian [1 ]
Li, Jing [1 ]
Gao, Qinghe [1 ]
Zhang, Tao [1 ]
Fang, Lizhen [1 ]
机构
[1] Xinxiang Med Univ, Sch Pharm, Xinxiang 453003, Henan, Peoples R China
[2] Yanbian Univ, Coll Med, Yanji 133002, Jilin, Peoples R China
关键词
MINISCI-TYPE ALKYLATION; ALIPHATIC-ALDEHYDES; HETEROCYCLES; ROUTE;
D O I
10.1039/d3cc00906h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A protocol for visible-light-induced C-H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This protocol allows the green, mild, and efficient functionalization of various purine nucleosides with a broad range of alkyl and aryl aldehydes.
引用
收藏
页码:3910 / 3913
页数:4
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