Photocatalyst-free visible-light-induced highly selective acylation of purine nucleosides at the C6 position

被引:10
|
作者
Li, Luohao [1 ]
Zheng, Huiqin [1 ]
Guo, Feixiang [1 ]
Fang, Zehui [2 ]
Sun, Qianqian [1 ]
Li, Jing [1 ]
Gao, Qinghe [1 ]
Zhang, Tao [1 ]
Fang, Lizhen [1 ]
机构
[1] Xinxiang Med Univ, Sch Pharm, Xinxiang 453003, Henan, Peoples R China
[2] Yanbian Univ, Coll Med, Yanji 133002, Jilin, Peoples R China
关键词
MINISCI-TYPE ALKYLATION; ALIPHATIC-ALDEHYDES; HETEROCYCLES; ROUTE;
D O I
10.1039/d3cc00906h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A protocol for visible-light-induced C-H acylation selectively at the C6 position of purine nucleosides with aldehydes under photocatalyst-free conditions was established herein. This protocol allows the green, mild, and efficient functionalization of various purine nucleosides with a broad range of alkyl and aryl aldehydes.
引用
收藏
页码:3910 / 3913
页数:4
相关论文
共 50 条
  • [21] Visible-Light-Induced Photocatalyst-Free Oxidative Cyclization of Primary Alcohols by Selectfluor via HAT Process: Synthesis of Quinazolinones and Benzothiadiazines
    Prasanth, Kesavan
    Reddy, Mandapati Bhargava
    Anandhan, Ramasamy
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 11 (01)
  • [22] Visible-light-induced iminyl radical formation via electron-donor-acceptor complexes: a photocatalyst-free approach to phenanthridines and quinolines
    Sun, Jingjing
    He, Yanyan
    An, Xiao-De
    Zhang, Xu
    Yu, Lei
    Yu, Shouyun
    ORGANIC CHEMISTRY FRONTIERS, 2018, 5 (06): : 977 - 981
  • [23] Visible-light induced disproportionation of pyrrole derivatives for photocatalyst-free aryl halides reduction
    Li, Zhi-Jun
    Li, Shuya
    Hofman, Elan
    Davis, Andrew Hunter
    Leem, Gyu
    Zheng, Weiwei
    GREEN CHEMISTRY, 2020, 22 (06) : 1911 - 1918
  • [24] Visible-light-induced direct perfluoroalkylation/heteroarylation of [1.1.1]propellane to diverse bicyclo[1.1.1]pentanes (BCPs) under metal and photocatalyst-free conditions
    Zhu, Jiashun
    Guo, Yirui
    Zhang, Yuru
    Li, Wanmei
    Zhang, Pengfei
    Xu, Jun
    GREEN CHEMISTRY, 2023, 25 (03) : 986 - 992
  • [25] Visible-light-induced decarboxylative acylation of quinoxalin-2(1H)-ones with α-oxo carboxylic acids under metal-, strong oxidant- and external photocatalyst-free conditions
    Xie, Long-Yong
    Bai, You-Shu
    Xu, Xiang-Qin
    Peng, Xia
    Tang, Hai-Shan
    Huang, Ying
    Lin, Ying-Wu
    Cao, Zhong
    He, Wei-Min
    GREEN CHEMISTRY, 2020, 22 (05) : 1720 - 1725
  • [26] Visible-light-induced tandem cyclization of 2-alkynylanilines with disulfides: a convenient method for accessing benzothiophenes under transition-metal-free and photocatalyst-free conditions
    Xie, Xiaoyu
    Li, Pinhua
    Shi, Qing
    Wang, Lei
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 15 (36) : 7678 - 7684
  • [27] A photocatalyst-free method for the synthesis of 6-alkyl(aryl)phenanthridines under visible light irradiation
    Natarajan, Palani
    Partigya
    Pooja
    NEW JOURNAL OF CHEMISTRY, 2022, 46 (47) : 22862 - 22868
  • [28] Photocatalyst-Free Regioselective C-H Thiocyanation of 4-Anilinocoumarins under Visible Light
    Li, Guoqing
    Yan, Qiuli
    Gong, Xueqin
    Dou, Xiaomeng
    Yang, Daoshan
    ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2019, 7 (16): : 14009 - 14015
  • [29] Visible-Light-Induced Decarboxylative Acylation of Pyridine N-Oxides with α-Oxocarboxylic Acids Using Fluorescein Dimethylammonium as a Photocatalyst
    Hou, Chuanfu
    Sun, Shouneng
    Liu, Ziqi
    Zhang, Hui
    Liu, Yue
    An, Qi
    Zhao, Jian
    Ma, Junjie
    Sun, Zhizhong
    Chu, Wenyi
    ADVANCED SYNTHESIS & CATALYSIS, 2021, 363 (11) : 2806 - 2812
  • [30] Metal-Free, Visible-Light-Induced Selective C-C Bond Cleavage of Cycloalkanones with Molecular Oxygen
    Guo, Li-Na
    Xin, Hong
    Duan, Xin-Hua
    Liu, Le
    CHEMISTRY-A EUROPEAN JOURNAL, 2020, 26 (51) : 11690 - 11694