Mitochondria-targeted fluorophores for in vivo NIR-II imaging-guided PDT/PTT

被引：22
|
作者：
Ding, Qihang [1 ]
Mei, Ling [4 ]
Liu, Yu [2 ,3 ]
Zhou, Shan [2 ,3 ]
Chen, Lu [2 ,3 ]
Liang, Yuying [2 ,3 ]
Li, Mingle [1 ]
Zhou, Hui [2 ,3 ]
Yin, Chao [2 ,3 ]
Kim, Jong Seung [1 ]
机构：
[1] Korea Univ, Dept Chem, Seoul 02841, South Korea
[2] Nanjing Univ Posts & Telecommun, Inst Adv Mat IAM, State Key Lab Organ Elect & Informat Displays, 9 Wenyuan Rd, Nanjing 210023, Peoples R China
[3] Nanjing Univ Posts & Telecommun, Inst Adv Mat IAM, 9 Wenyuan Rd, Nanjing 210023, Peoples R China
[4] Chengdu Univ, Sichuan Ind Inst Antibiot, Engn Res Ctr Pharmaceut & Equipment Sichuan Prov, Sch Pharm, Chengdu 610106, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 52期
基金：
新加坡国家研究基金会; 中国国家自然科学基金;
关键词：
PHOTODYNAMIC THERAPY;
D O I：
10.1039/d3cc02380j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple yet powerful D-A type-based NIR-II fluorophore (MTF) with mitochondria targeting was constructed. This mitochondrial targeting dye MTF exhibited not only a photothermal effect but also photodynamic performance, and was further fabricated with DSPE-mPEG to generate nanodots for in vivo experiments, achieving strong NIR-II fluorescence tracing of tumors and impressive NIR-II image-guided photodynamic therapy (PDT) and photothermal therapy (PTT).
引用
收藏
页码：8127 / 8130
页数：4
相关论文
共 50 条
  • [31] NIR-II Fluorescence Imaging-guided Photothermal Activated Pyroptosis For Precision Therapy Of Glioma
    Chen, Zhuang
    Luo, Yi
    Jia, Qian
    Yang, Zuo
    Liu, Zebing
    Cui, Can
    Qiao, Chaoqiang
    Yang, Peng
    Wang, Zhongliang
    CHEMBIOCHEM, 2025, 26 (04)
  • [32] Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics
    Roy, Shubham
    Bag, Neelanjana
    Bardhan, Souravi
    Hasan, Ikram
    Guo, Bing
    ADVANCED DRUG DELIVERY REVIEWS, 2023, 197
  • [33] Initial Experience of NIR-II Fluorescence Imaging-Guided Surgery in Foot and Ankle Surgery
    Fan, Xiaoxiao
    Yang, Jie
    Ni, Huwei
    Xia, Qiming
    Liu, Xiaolong
    Wu, Tianxiang
    Li, Lin
    Prasad, Paras N.
    Liu, Chao
    Lin, Hui
    Qian, Jun
    ENGINEERING, 2024, 40 : 19 - 27
  • [34] A PEGylated conjugated-BODIPY oligomer for NIR-II imaging-guided photothermal therapy
    Wang, Yuan
    Shan, Tongtong
    Zheng, Jiahao
    Tian, Jia
    Zhang, Weian
    JOURNAL OF MATERIALS CHEMISTRY B, 2025,
  • [35] NIR-II imaging-guided photothermal cancer therapy combined with enhanced immunogenic death
    Wang, Yukun
    Li, Wenjing
    Lin, Bi
    Yuan, Ying
    Ning, Pengbo
    Tao, Xiaofeng
    Lv, Ruichan
    BIOMATERIALS SCIENCE, 2023, 11 (15) : 5177 - 5185
  • [36] Multifunctional Nanotheranostic Agent for NIR-II Imaging-Guided Synergetic Photothermal/Photodynamic Therapy
    Li, Tuanwei
    Liu, Le
    Xu, Pengping
    Yuan, Pan
    Tian, Youliang
    Cheng, Quan
    Yan, Lifeng
    ADVANCED THERAPEUTICS, 2021, 4 (03)
  • [37] A NIR-II Fluorophores for Multiple Myeloma Imaging and Photodynamic Therapy
    Jiang, Hongqiang
    Ding, Qihang
    Li, Qianqian
    Wei, Yongchang
    Hong, Xuechuan
    Zhou, Fuling
    BLOOD, 2021, 138
  • [38] A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection
    Huang, Yue
    Li, Dan
    Wang, Deliang
    Chen, Xiaohui
    Ferreira, Lino
    Martins, M. Cristina L.
    Wang, Youxiang
    Jin, Qiao
    Wang, Dong
    Tang, Ben Zhong
    Ji, Jian
    BIOMATERIALS, 2022, 286
  • [39] Recent Progress of Cyanine Fluorophores for NIR-II Sensing and Imaging
    Zhou, Hui-Jie
    Ren, Tian-Bing
    CHEMISTRY-AN ASIAN JOURNAL, 2022, 17 (08)
  • [40] Novel aza-BODIPY based small molecular NIR-II fluorophores for in vivo imaging
    Bai, Lei
    Sun, Pengfei
    Liu, Yi
    Zhang, Hang
    Hu, Wenbo
    Zhang, Wansu
    Liu, Zhipeng
    Fan, Quli
    Li, Lin
    Huang, Wei
    CHEMICAL COMMUNICATIONS, 2019, 55 (73) : 10920 - 10923
12345