Development of a two-photon fluorescent probe for imaging hydrogen sulfide (H2S) in living cells and zebrafish

被引:13
|
作者
Xu, Chen [1 ]
Zhang, Yukun [1 ]
Sun, Hui [1 ]
Ai, Jindong [1 ]
Ren, Mingguang [1 ]
机构
[1] Qilu Univ Technol, Shandong Acad Sci, State Key Lab Biobased Mat & Green Papermaking, Key Lab Pulp & Paper Sci & Technol Shandong Prov,M, Jinan 250353, Peoples R China
基金
中国国家自然科学基金;
关键词
CYSTEINE;
D O I
10.1039/d3ay00375b
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We present a new two-photon fluorescent probe (T-HS) for the detection of H2S. With the addition of hydrogen sulfide, the absorption and fluorescence spectra of the probe show regular changes. The probe exhibited favorable properties, such as large turn-on fluorescence signal, good selectivity and low cytotoxicity. Moreover, the probe T-HS was successfully used for the fluorescence imaging of H2S in live cells and zebrafish.
引用
收藏
页码:1948 / 1952
页数:5
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