Highly selective two-photon fluorescent probe for imaging of nitric oxide in living cells

被引:0
|
作者
Qing Liu [1 ,2 ]
Lin Xue [1 ]
Dong-Jian Zhu [1 ,2 ]
Guo-Ping Li [1 ,2 ]
Hua Jiang [1 ,3 ]
机构
[1] Beijing National Laboratory for Molecular Sciences,CAS Key Laboratory of Photochemistry,Institute of Chemistry,Chinese Academy of Sciences
[2] University of Chinese Academy of Sciences
[3] College of Chemistry,Beijing Normal University
基金
中国国家自然科学基金;
关键词
Fluorescent probe Nitric oxide Fluorescence imaging One-photon microscopy Two-photon microscopy;
D O I
暂无
中图分类号
O657.3 [光化学分析法(光谱分析法)];
学科分类号
070302 ; 081704 ;
摘要
A new two-photon fluorescent probe, ADNO, for nitric oxide(NO) based on intramolecular photoinduced electron transfer(PET) mechanism displays a rapid response to NO with a remarkable fluorescent enhancement in PBS buffer. The excellent chemoselectivity of ADNO for NO over other ROS/RNS(reactive oxygen species or nitrogen species) and common metal ions was observed. Moreover, ADNO has been successfully applied in fluorescence imaging of NO of living cells using both one-photon microscopy(OPM) and two-photon microscopy(TPM).
引用
收藏
页码:19 / 23
页数:5
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