Recent updates in nanotechnological advances for wound healing: A narrative review

被引:6
|
作者
Chopra, Hitesh [3 ]
Mohanta, Yugal Kishore [1 ,2 ]
Mahanta, Saurov [4 ]
Mohanta, Tapan Kumar [5 ]
Singh, Inderbir [3 ]
Avula, Satya Kumar [5 ]
Mallick, Sarada Prasanna [6 ]
Rabaan, Ali A. [7 ,8 ,9 ]
Alsaihati, Hajir [10 ]
Alsayyah, Ahmed [11 ]
Alissa, Mohammed [12 ]
Alturaifi, Hussain R. [13 ]
Alalwan, Bader [14 ]
Attia, Mohamed S. [15 ]
Chakraborty, Sandip [16 ]
Dhama, Kuldeep [17 ]
机构
[1] Univ Sci & Technol Meghalaya USTM, Sch Biol Sci, Dept Appl Biol, Nanobiotechnol & Translat Knowledge Lab, 9th Mile,Ri-Bhoi, Techno City 793101, Meghalaya, India
[2] Chettinad Hosp & Res Inst, Chettinad Acad Res & Educ, Ctr Herbal Pharmacol & Environm Sustainabil, Kelambakkam 603103, Tamil Nadu, India
[3] Chitkara Univ, Chitkara Coll Pharm, Dept Pharmaceut, Rajpura 140401, Punjab, India
[4] Natl Inst Elect & Informat Technol NIELIT, Guwahati Ctr, Bioinformat Div, Gauhati, India
[5] Univ Nizwa, Biotech & Om Lab, Nat & Med Sci Res Ctr, Nizwa 616, Oman
[6] Koneru Lakshmaiah Educ Fdn, Dept Biotechnol, Guntur 522302, Andhra Pradesh, India
[7] Johns Hopkins Aramco Healthcare, Mol Diagnost Lab, Dhahran 31311, Saudi Arabia
[8] Alfaisal Univ, Coll Med, Riyadh 11533, Saudi Arabia
[9] Univ Haripur, Dept Publ Hlth & Nutr, Haripur 22610, Pakistan
[10] Univ Hafr Al Batin, Coll Appl Med Sci, Dept Clin Lab Sci, Hafar al Batin 39831, Saudi Arabia
[11] Imam Abdulrahman Bin Faisal Univ, Coll Med, Pathol Dept, Dammam 31441, Saudi Arabia
[12] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Dept Med Lab Sci, Alkharj 11942, Saudi Arabia
[13] King Fahad Hosp, Dept Lab & Blood Bank, Al Hufuf, Saudi Arabia
[14] MohammedAl Mana Coll Med Sci, Clin Lab Sci Dept, Dammam 34222, Saudi Arabia
[15] Zagazig Univ, Fac Pharm, Dept Pharmaceut, Zagazig, Egypt
[16] Coll Vet Sci & Anim Husb, Dept Vet Microbiol, RK Nagar, RK Nagar 799008, Tripura, India
[17] ICAR Indian Vet Res Inst, Div Pathol, Izatnagar, Uttar Pradesh, India
关键词
nanoformulations; wound healing; nanoparticles; nanomaterials; hydrogels; PSEUDOMONAS-AERUGINOSA ELASTASE; SILVER NANOPARTICLES; BACTERIAL PROTEASES; ANTIBACTERIAL ACTIVITY; CONTROLLED-RELEASE; STAPHYLOCOCCUS-AUREUS; INJECTABLE HYDROGELS; NANOFIBER SCAFFOLD; ASTRAGALOSIDE IV; BROAD-SPECTRUM;
D O I
10.1515/ntrev-2023-0129
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The repair and remodeling of injured tissues, known as wound healing, is a multifaceted process. The use of nanotechnology to speed up the healing process of wounds by promoting the right kind of mobility through different mechanisms has shown a lot of promise. Several nanotechnologies with novel properties have emerged in recent years, each of which targets a different issue associated with wound-healing processes. Through their antibacterial, anti-inflammatory, and angiogenic actions, nanomaterials may alter the wound microenvironment from a non-healing to a healing state. Wound dressings including hydrogels, gelatin sponges, films, and bandages may all benefit from the use of nanoparticles (NPs) to keep harmful microbes out. The addition of bioactive substances like antibiotics, NPs, and growth factors to certain dressings may further boost their efficacy. In conclusion, this review sheds light on wound healing that may be aided by the special features of materials based on nanotechnology. Although nanomaterials for wound healing show great promise, further study is needed before this promising area can convert its findings into consumer-friendly solutions.
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页数:34
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