New unexpected role for Wolfram Syndrome protein WFS1: a novel therapeutic target for Alzheimer's disease?

被引：3
|
作者：
Chen, Shuo [1 ]
Acosta, Diana [2 ]
Fu, Hongjun [2 ]
机构：
[1] Ohio State Univ, Dept Neurosci, Biomed Sci Grad Program, Columbus, OH USA
[2] Ohio State Univ, Dept Neurosci, Columbus, OH 43210 USA
来源：
NEURAL REGENERATION RESEARCH | 2023年 / 18卷 / 07期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.4103/1673-5374.361540
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：1501 / 1502
页数：2
相关论文
共 50 条
  • [31] Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome
    Luuk, Hendrik
    Koks, Sulev
    Plaas, Mario
    Hannibal, Jens
    Rehfeld, Jens F.
    Vasar, Eero
    JOURNAL OF COMPARATIVE NEUROLOGY, 2008, 509 (06) : 642 - 660
  • [32] A novel heterozygous mutation of the WFS1 gene leading to constitutive endoplasmic reticulum stress is the cause of Wolfram syndrome
    Morikawa, Shuntaro
    Tajima, Toshihiro
    Nakamura, Akie
    Ishizu, Katsura
    Ariga, Tadashi
    PEDIATRIC DIABETES, 2017, 18 (08) : 934 - 941
  • [33] A novel mutation of WFS1 gene in a Japanese man of Wolfram syndrome with positive diabetes-related antibodies
    Nakamura, Akinobu
    Shimizu, Chikara
    Nagai, So
    Taniguchi, Satoshi
    Umetsu, Masaaki
    Atsumi, Toshiya
    Wada, Norio
    Yoshioka, Narihito
    Ono, Yuri
    Tanizawa, Yukio
    Koike, Takao
    DIABETES RESEARCH AND CLINICAL PRACTICE, 2006, 73 (02) : 215 - 217
  • [34] Mutational spectrum of the WFS1 gene in Wolfram syndrome, nonsyndromic hearing impairment, diabetes mellitus, and psychiatric disease
    Cryns, K
    Sivakumaran, TA
    Van den Ouweland, JMW
    Pennings, RJE
    Cremers, CWRJ
    Flothmann, K
    Young, TL
    Smith, RJH
    Lesperance, MM
    Van Camp, G
    HUMAN MUTATION, 2003, 22 (04) : 275 - 287
  • [35] Mutation analysis of the WFS1 gene in seven Danish Wolfram syndrome families; four new mutations identified
    Hansen, L
    Eiberg, H
    Barrett, T
    Bek, T
    Kjærsgaard, P
    Tranebjærg, L
    Rosenberg, T
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2005, 13 (12) : 1275 - 1284
  • [36] Mutation analysis of the WFS1 gene in seven Danish Wolfram syndrome families; four new mutations identified
    Lars Hansen
    Hans Eiberg
    Timothy Barrett
    Toke Bek
    Per Kjærsgaard
    Lisbeth Tranebjærg
    Thomas Rosenberg
    European Journal of Human Genetics, 2005, 13 : 1275 - 1284
  • [37] Role of Serotonin in Alzheimer's Disease A New Therapeutic Target?
    Geldenhuys, Werner J.
    Van der Schyf, Cornelis J.
    CNS DRUGS, 2011, 25 (09) : 765 - 781
  • [38] Molecular characterization of WFS1 in an Iranian family with Wolfram syndrome reveals a novel frameshift mutation associated with early symptoms
    Sobhani, Maryam
    Tabatabaiefar, Mohammad Amin
    Rajab, Asadollah
    Kajbafzadeh, Abdol-Mohammad
    Noori-Daloii, Mohammad Reza
    GENE, 2013, 528 (02) : 309 - 313
  • [39] Novel homozygous mutation in exon 5 of WFS1 gene in an Apulian family with mild phenotypic expression of Wolfram syndrome
    Piccinno, E.
    Ortolani, F.
    Vendemiale, M.
    Tummolo, A.
    Masciopinto, M.
    Natale, M. P.
    De Luca, A.
    Agolini, E.
    Aloi, C.
    Salina, A.
    D'Annunzio, G.
    Fischetto, R.
    Papadia, F.
    CLINICAL GENETICS, 2014, 86 (02) : 197 - 198
  • [40] Maternal uniparental disomy of chromosome 4 and homozygous novel mutation in the WFS1 gene in a paediatric patient with Wolfram syndrome
    Papadimitriou, D. T.
    Manolakos, E.
    Bothou, C.
    Zoupanos, G.
    Papoulidis, I.
    Orru, S.
    Skarmoutsos, F.
    Delides, A.
    Bakoula, C.
    Papadimitriou, A.
    Urano, F.
    DIABETES & METABOLISM, 2015, 41 (05) : 433 - 435
12345