Probabilistic benefit-risk analysis of fish: Nutritional benefit versus methylmercury-contaminated risk

被引:1
|
作者
Lin, Pinpin [1 ]
Lee, Pei-, I [2 ]
Ling, Min-Pei [3 ]
机构
[1] Natl Hlth Res Inst, Natl Inst Environm Hlth Sci, Zhunan, Miaoli Cty, Taiwan
[2] Natl Taiwan Ocean Univ, Inst Food Safety & Risk Assessment, Keelung, Taiwan
[3] Natl Taiwan Ocean Univ, Dept Food Sci, Keelung, Taiwan
关键词
Benefit-risk analysis; Methylmercury; Risk assessment; Hazard quotient; Disability adjusted life years; POLYUNSATURATED FATTY-ACIDS; TOTAL MERCURY; HEALTH-RISK; CONSUMPTION; EXPOSURE; DIOXIN; CHILDREN;
D O I
10.1016/j.marpolbul.2023.115179
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This paper carries out probabilistic approach to quantify the benefit-risk analysis for foods (BRAFO) of omega-3 polyunsaturated fatty acid and methylmercury (MeHg) for the people who eat the mercury-contaminated fish in Taiwan. We applied the hazard quotient (HQ) model to assess the risk of developmental neuropsychological impairment effect and the desirable dose index (DI) model to quantify the health benefits. Besides, we also applied the disability adjusted life years (DALY) model to assess the number of years lost by incidence of affected infants' intelligence quotient (IQ) and coronary heart disease (CHD) or Stroke for adult. The results of this study show that although the risk of cod and scad are higher, Taiwan residents do not need to reduce intake rate based on benefit considerations. Furthermore, according to the benefits of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), this study suggests that more intake of saury and salmon.
引用
收藏
页数:10
相关论文
共 50 条
  • [31] BENEFIT-RISK ASSESSMENT TODAY
    HALL, RE
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1978, 55 (01) : 193 - 197
  • [32] Tetrabamate and a benefit-risk ratio
    Lucena, MI
    Andrade, RJ
    García-Ruiz, E
    Madurga, M
    MEDICINA CLINICA, 2002, 118 (12): : 477 - 477
  • [33] Benefit-Risk Assessment of Fish Oil in Preventing Cardiovascular Disease
    Lands, Bill
    DRUG SAFETY, 2016, 39 (09) : 787 - 799
  • [34] From fish chemical characterisation to the benefit-risk assessment - Part A
    Afonso, Claudia
    Lourenco, Helena Maria
    Cardoso, Carlos
    Bandarra, Narcisa Maria
    Carvalho, Maria Luisa
    Castro, Matilde
    Nunes, Maria Leonor
    FOOD CHEMISTRY, 2013, 137 (1-4) : 99 - 107
  • [35] Structured benefit-risk evaluation for medicinal products: review of quantitative benefit-risk assessment findings in the literature
    Kurzinger, Marie-Laure
    Douarin, Ludivine
    Uzun, Ievgeniia
    El-Haddad, Chantal
    Hurst, William
    Juhaeri, Juhaeri
    Tcherny-Lessenot, Stephanie
    THERAPEUTIC ADVANCES IN DRUG SAFETY, 2020, 11
  • [36] FDA's Benefit-Risk Framework for Human Drugs and Biologics: Role in Benefit-Risk Assessment and Analysis of Use for Drug Approvals
    Lackey, Leila
    Thompson, Graham
    Eggers, Sara
    THERAPEUTIC INNOVATION & REGULATORY SCIENCE, 2021, 55 (01) : 170 - 179
  • [37] Quantitative Benefit-Risk Analysis for Evaluating Drug Therapies
    Kodell, Ralph L.
    Chen, James J.
    JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2013, 23 (01) : 231 - 238
  • [38] State of the art in benefit-risk analysis: Food microbiology
    Magnusson, S. H.
    Gunnlaugsdottir, H.
    van Loveren, H.
    Holm, F.
    Kalogeras, N.
    Leino, O.
    Luteijn, J. M.
    Odekerken, G.
    Pohjola, M. V.
    Tijhuis, M. J.
    Tuomisto, J. T.
    Ueland, O.
    White, B. C.
    Verhagen, H.
    FOOD AND CHEMICAL TOXICOLOGY, 2012, 50 (01) : 33 - 39
  • [39] State of the art in benefit-risk analysis: Food and nutrition
    Tijhuis, M. J.
    de Jong, N.
    Pohjola, M. V.
    Gunnlaugsdottir, H.
    Hendriksen, M.
    Hoekstra, J.
    Holm, F.
    Kalogeras, N.
    Leino, O.
    van Leeuwen, F. X. R.
    Luteijn, J. M.
    Magnusson, S. H.
    Odekerken, G.
    Rompelberg, C.
    Tuomisto, J. T.
    Ueland, O.
    White, B. C.
    Verhagen, H.
    FOOD AND CHEMICAL TOXICOLOGY, 2012, 50 (01) : 5 - 25
  • [40] Benefit-risk analysis: examples using quantitative methods
    Holden, WL
    Juhaeri, J
    Dai, WJ
    PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2003, 12 (08) : 693 - 697