A ratiometric fluorescent probe for fast detection and bioimaging of formaldehyde

被引：11
|
作者：
Lin, Nai-Jie [1 ]
Wu, Huan [1 ]
Peng, Jing [1 ]
Yang, Shu-Han [1 ]
Tan, Rui [1 ]
Peng, Yu [1 ]
Wang, Ya-Wen [1 ]
机构：
[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Sch Chem, Chengdu 610031, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 10期
基金：
中国国家自然科学基金;
关键词：
ENDOGENOUS FORMALDEHYDE; SELECTIVE DETECTION; TISSUES; BRAIN;
D O I：
10.1039/d2ob02314h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel ratiometric probe (SWJT-10) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueous solution. And it showed good selectivity, high sensitivity and a fast response to FA (less than 5 s) due to a new recognition mechanism. Moreover, SWJT-10 has been applied to monitor FA in living cells and zebrafish.
引用
收藏
页码：2167 / 2171
页数：5
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