INTRA-ARTICULAR MM-II, A NOVEL SUSPENSION OF LARGE EMPTY MULTILAMELLAR LIPOSOMES, IN PAINFUL KNEE OSTEOARTHRITIS: A 26 WEEK PHASE 2B RANDOMIZED TRIAL

被引：0

作者：

Conaghan, P. G. ^{[1
]}

Rovsing, H. ^{[2
]}

Lau, E. ^{[3
]}

Boll, S. L. ^{[4
]}

Brahmachari, B. ^{[5
]}

Chou, R. C. ^{[5
]}

Joshi, T. ^{[5
]}

Wechsler, R. ^{[6
]}

Yao, S. L. ^{[5
]}

Weiner, S. ^{[5
]}

Bihlet, A. R. ^{[7
]}

Schnitzer, T. ^{[8
]}

机构：

[1] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, W Yorkshire, England

[2] Sanos Clin, Gandrup, Denmark

[3] Hong Kong Ctr Clin Res, Hong Kong, Peoples R China

[4] Sanos Clin, Vejle, Denmark

[5] Sun Pharmaceut Inc, Princeton, NJ USA

[6] Moebius Med Ltd, Tel Aviv, Israel

[7] NBCD, Soborg, Denmark

[8] Northwestern Univ, Feinberg Sch Med, Chicago, IL USA

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2023年 / 82卷

关键词：

Osteoarthritis; Clinical Trials;

D O I：

10.1136/annrheumdis-2023-eular.5397

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

POS0106

引用

页码：266 / 267

页数：2

共 48 条

[31] Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
Lamo-Espinosa, Jose M.
Mora, Gonzalo
Blanco, Juan F.
Granero-Molto, Froilan
Nunez-Cordoba, Jorge M.
Sanchez-Echenique, Carmen
Bondia, Jose M.
Aquerreta, Jesus Damaso
Andreu, Enrique J.
Ornilla, Enrique
Villaron, Eva M.
Valenti-Azcarate, Andres
Sanchez-Guijo, Fermin
Consuelo del Canizo, Maria
Ramon Valenti-Nin, Juan
Prosper, Felipe
JOURNAL OF TRANSLATIONAL MEDICINE, 2016, 14
[32] Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
José M. Lamo-Espinosa
Gonzalo Mora
Juan F. Blanco
Froilán Granero-Moltó
Jorge M. Nuñez-Córdoba
Carmen Sánchez-Echenique
José M. Bondía
Jesús Dámaso Aquerreta
Enrique J. Andreu
Enrique Ornilla
Eva M. Villarón
Andrés Valentí-Azcárate
Fermín Sánchez-Guijo
María Consuelo del Cañizo
Juan Ramón Valentí-Nin
Felipe Prósper
Journal of Translational Medicine, 14
[33] Intra-articular implantation of autologous bone marrow-derived mesenchymal stromal cells to treat knee osteoarthritis: a randomized, triple-blind, placebo-controlled phase 1/2 clinical trial
Emadedin, Mohsen
Labibzadeh, Narges
Liastani, Maede Ghorbani
Karimi, Aliasghar
Jaroughi, Neda
Bolurieh, Tina
Hosseini, Seyyedeh-Esmat
Baharvand, Hossein
Aghdami, Nasser
CYTOTHERAPY, 2018, 20 (10) : 1238 - 1246
[34] Efficacy of a Novel Intra-Articular Administration of Platelet-Rich Plasma One-Week Prior to Hyaluronic Acid versus Platelet-Rich Plasma Alone in Knee Osteoarthritis: A Prospective, Randomized, Double-Blind, Controlled Trial
Wu, Yung-Tsan
Li, Tsung-Ying
Lee, Kuei-Chen
Lam, King Hei Stanley
Chang, Chih-Ya
Chang, Cheng-Kuang
Chen, Liang-Cheng
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (11)
[35] Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial
Cheng-Fong Chen
Chih-Chien Hu
Chen-Te Wu
Hung-Ta H. Wu
Chun-Shin Chang
Yi-Pei Hung
Chia-Chu Tsai
Yuhan Chang
Stem Cell Research & Therapy, 12
[36] Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial
Chen, Cheng-Fong
Hu, Chih-Chien
Wu, Chen-Te
Wu, Hung-Ta H.
Chang, Chun-Shin
Hung, Yi-Pei
Tsai, Chia-Chu
Chang, Yuhan
STEM CELL RESEARCH & THERAPY, 2021, 12 (01)
[37] Treatment of Knee Osteoarthritis with SM04690 Improved WOMAC A1 "Pain on Walking" - Results from a 52-Week, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of a Novel, Intra-Articular, Wnt Pathway Inhibitor
Tambiah, Jeyanesh
Kennedy, Sarah
Ghandehari, Heli
Swearingen, Christopher
Hochberg, Marc C.
ARTHRITIS & RHEUMATOLOGY, 2018, 70
[38] EFFICACY OUTCOMES IN PATIENTS WITH KNEE OSTEOARTHRITIS: PER-PROTOCOL ANALYSES FROM SPRINGBOARD, A PHASE 2, RANDOMIZED, 24-WEEK STUDY OF EP-104IAR (LONG-ACTING INTRA-ARTICULAR INJECTION OF FLUTICASONE PROPIONATE)
Helliwell, James A.
Malone, Amanda
Kowalski, Mark M.
Rovsing, Helene
Boll, Sidsel Lynggard
Bihlet, Asger R.
Miller, Claire Prener
Mondragon, Alejandro Castillo
Li, Yanqi
Dobek, Christine
Peck, Vik
Wilmink, Mike
Conaghan, Philip
Simon, Lee S.
OSTEOARTHRITIS AND CARTILAGE, 2024, 32 : S48 - S49
[39] SAFETY, CLINICAL AND IMAGING OUTCOMES OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT INHIBITOR (SM04690) IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE: EXPLORATORY ANALYSIS OF RESULTS FROM A 24 WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 1 STUDY
Yazici, Y.
McAlindon, T. E.
Fleischmann, R. M.
Gibofsky, A.
Lane, N. E.
Kivitz, A. J.
Majumdar, S.
Strand, V.
Swearingen, C. J.
DiFrancesco, A.
Tambiah, J.
Hood, J.
Hochberg, M. C.
ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 : 826 - 826
[40] Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II)
Maria Lamo-Espinosa, Jose
Mora, Gonzalo
Blanco, Juan F.
Granero-Molto, Froilan
Maria Nunez-Cordoba, Jorge
Lopez-Elio, Silvia
Andreu, Enrique
Sanchez-Guijo, Fermin
Damaso Aquerreta, Jose
Maria Bondia, Jose
Valenti-Azcarate, Andres
del Consuelo del Canizo, Maria
Maria Villaron, Eva
Ramon Valenti-Nin, Juan
Prosper, Felipe
JOURNAL OF TRANSLATIONAL MEDICINE, 2018, 16

← 1 2 3 4 5 →