SAFETY, CLINICAL AND IMAGING OUTCOMES OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT INHIBITOR (SM04690) IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE: EXPLORATORY ANALYSIS OF RESULTS FROM A 24 WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 1 STUDY

被引：0

作者：

Yazici, Y. ^{[1
]}

McAlindon, T. E. ^{[2
]}

Fleischmann, R. M. ^{[3
]}

Gibofsky, A. ^{[4
]}

Lane, N. E. ^{[5
]}

Kivitz, A. J. ^{[6
]}

Majumdar, S. ^{[7
]}

Strand, V. ^{[8
]}

Swearingen, C. J. ^{[1
]}

DiFrancesco, A. ^{[1
]}

Tambiah, J. ^{[1
]}

Hood, J. ^{[1
]}

Hochberg, M. C. ^{[9
]}

机构：

[1] Samumed LLC, San Diego, CA USA

[2] Tufts Med Ctr, Boston, MA USA

[3] Metroplex Clin Res Ctr, Dallas, TX USA

[4] Hosp Special Surg, 535 E 70th St, New York, NY 10021 USA

[5] Univ Calif Davis, Davis, CA 95616 USA

[6] Altoona Arthrit & Osteoporosis Ctr, Altoona, PA USA

[7] Univ Calif San Francisco, San Francisco, CA 94143 USA

[8] Stanford Univ, Palo Alto, CA 94304 USA

[9] Univ Maryland, Med Ctr, Baltimore, MD 21201 USA

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2016年 / 75卷

关键词：

D O I：

10.1136/annrheumdis-2016-eular.1735

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

SAT0428

引用

页码：826 / 826

页数：1

共 50 条

[1] Radiographic Outcomes from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee
Swearingen, Christopher J.
Majumdar, Sharmila
Simsek, Ismail
DiFrancesco, Anita
Tambiah, Jeymi
Yazici, Yusuf
ARTHRITIS & RHEUMATOLOGY, 2016, 68
[2] Safety, Efficacy and Biomarker Outcomes of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
Yazici, Yusuf
McAlindon, Timothy E.
Fleischmann, Roy
Gibofsky, Allan
Lane, Nancy E.
Kivitz, Alan J.
Skrepnik, Nebojsa
Armas, Eddie
Swearingen, Christopher J.
DiFrancesco, Anita
Tambiah, Jeyanesh R. S.
Hood, John
Hochberg, Marc C.
ARTHRITIS & RHEUMATOLOGY, 2015, 67
[3] CLINICAL OUTCOMES FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2 STUDY OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT PATHWAY INHIBITOR (SM04690) FOR THE TREATMENT OF KNEE OSTEOARTHRITIS: WEEK 26 INTERIM ANALYSIS
Yazici, Y.
Gibofsky, A.
Lane, N. E.
Skrepnik, N.
Armas, E.
Swearingen, C. J.
DiFrancesco, A.
Tambiah, J. R.
McAlindon, T. E.
ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 985 - 986
[4] Results from a 52 Week Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of a Novel, Intra-Articular, Wnt Pathway Inhibitor (SM04690) for the Treatment of Knee Osteoarthritis
Yazici, Yusuf
McAlindon, Timothy E.
Gibofsky, Allan
Lane, Nancy E.
Clauw, Daniel J.
Armas, Eddie
Skrepnik, Nebojsa
Swearingen, Christopher J.
DiFrancesco, Anita
Tambiah, Jeymi
Hochberg, Marc
ARTHRITIS & RHEUMATOLOGY, 2017, 69
[5] RADIOGRAPHIC OUTCOMES FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2 STUDY OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT PATHWAY INHIBITOR (SM04690) IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE: WEEK 26 INTERIM ANALYSIS
Yazici, Y.
McAlindon, T. E.
Gibofsky, A.
Lane, N. E.
Skrepnik, N.
Armas, E.
Swearingen, C. J.
DiFrancesco, A.
Tambiah, J. R.
Hochberg, M. C.
ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 121 - 121
[6] RESULTS FROM A 52-WEEK RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2 STUDY OF A NOVEL, INTRA-ARTICULAR WNT PATHWAY INHIBITOR (SM04690) FOR THE TREATMENT OF KNEE OSTEOARTHRITIS
Yazici, Y.
McAlindon, T. E.
Gibofsky, A.
Lane, N. E.
Clauw, D. J.
Jones, M. H.
Bergfeld, J.
Swearingen, C. J.
DiFrancesco, A.
Tambiah, J. R.
Hochberg, M.
OSTEOARTHRITIS AND CARTILAGE, 2018, 26 : S293 - S294
[7] RESULTS FROM A 52-WEEK RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2 STUDYOFA NOVEL, INTRA-ARTICULAR WNT PATHWAY INHIBITOR (SM04690) FOR THE TREATMENT OF KNEE OSTEOARTHRITIS
Yazici, Y.
McAlindon, T.
Gibofsky, A.
Lane, N.
Clauw, D.
Grifman, M.
Swearingen, C.
DiFrancesco, A.
Tambiah, J.
Hochberg, M.
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2018, 24 : S137 - S137
[8] OMERACT-OARSI 'STRICT RESPONDERS' ANALYSIS FROM RESULTS OF A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 1 STUDY OF A NOVEL, INTRA-ARTICULAR, INJECTABLE, WNT INHIBITOR (SM04690) IN THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE
Yazici, Y.
Tambiah, J.
Swearingen, C. J.
DiFrancesco, A.
Strand, V.
OSTEOARTHRITIS AND CARTILAGE, 2016, 24 : S187 - S187
[9] Magnetic Resonance Imaging Outcomes Using an Intra-Articular Injection (SM04690) in the Treatment of Osteoarthritis of the Knee: Interim, Exploratory Analysis of Results from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study
Yazici, Yusuf
Majumdar, Sharmila
McAlindon, Timothy E.
Fleischmann, Roy
Gibofsky, Allan
Hochberg, Marc C.
Swearingen, Christopher J.
DiFrancesco, Anita
Tambiah, Jeyanesh R. S.
Hood, John
Lane, Nancy E.
ARTHRITIS & RHEUMATOLOGY, 2015, 67
[10] Analysis of Pain and Function Components in Omeract-Oarsi Strict Responders from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee
Strand, Vibeke
Swearingen, Christopher J.
Simsek, Ismail
DiFrancesco, Anita
Tambiah, Jeymi
Yazici, Yusuf
ARTHRITIS & RHEUMATOLOGY, 2016, 68

← 1 2 3 4 5 →