Asthma and allergic diseases: Cross talk of immune system and environmental factors

被引：4
|
作者：
Beerweiler, Claudia C. [1 ,4 ]
Masanetz, Rebecca K. [2 ,3 ]
Schaub, Bianca [1 ,4 ]
机构：
[1] Ludwig Maximilians Univ Munchen, Dr von Hauner Childrens Hosp, Univ Hosp, Pediat Allergol,Dept Pediat, Munich, Germany
[2] Friedrich Alexander Univ Erlangen Nurnberg, Dept Mol Neurol, Erlangen, Germany
[3] Univ Klinikum Erlangen, Erlangen, Germany
[4] Ludwig Maximilians Univ Munchen, German Ctr Lung Res DZL, Munich, Germany
来源：
EUROPEAN JOURNAL OF IMMUNOLOGY | 2023年 / 53卷 / 06期
关键词：
Air pollution; Allergy; Asthma; Environment; Immune regulation; FARM EXPOSURE; CHILDHOOD ASTHMA; PROTECT; CELLS; EXPRESSION; DUST;
D O I：
10.1002/eji.202249981
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Air pollution and immune-related diseases including allergy and asthma are constantly on the rise worldwide. Thus, a comprehensive investigation of environmentally induced immune regulation is required for a deeper understanding of disease pathogenesis, progression as well as prevention. Here, we summarize the current knowledge on environmental factors such as microbiome or geographical locations with harmful or protective effects for human health and their different routes of exposure. This review comprises a brief outline regarding the latest findings on the interaction of environmental factors with innate and adaptive regulation of the immune system, exemplarily for one protective and one harmful environmental factor, respectively.
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页数：7
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