Asthma and allergic diseases: Cross talk of immune system and environmental factors

被引:4
|
作者
Beerweiler, Claudia C. [1 ,4 ]
Masanetz, Rebecca K. [2 ,3 ]
Schaub, Bianca [1 ,4 ]
机构
[1] Ludwig Maximilians Univ Munchen, Dr von Hauner Childrens Hosp, Univ Hosp, Pediat Allergol,Dept Pediat, Munich, Germany
[2] Friedrich Alexander Univ Erlangen Nurnberg, Dept Mol Neurol, Erlangen, Germany
[3] Univ Klinikum Erlangen, Erlangen, Germany
[4] Ludwig Maximilians Univ Munchen, German Ctr Lung Res DZL, Munich, Germany
关键词
Air pollution; Allergy; Asthma; Environment; Immune regulation; FARM EXPOSURE; CHILDHOOD ASTHMA; PROTECT; CELLS; EXPRESSION; DUST;
D O I
10.1002/eji.202249981
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Air pollution and immune-related diseases including allergy and asthma are constantly on the rise worldwide. Thus, a comprehensive investigation of environmentally induced immune regulation is required for a deeper understanding of disease pathogenesis, progression as well as prevention. Here, we summarize the current knowledge on environmental factors such as microbiome or geographical locations with harmful or protective effects for human health and their different routes of exposure. This review comprises a brief outline regarding the latest findings on the interaction of environmental factors with innate and adaptive regulation of the immune system, exemplarily for one protective and one harmful environmental factor, respectively.
引用
收藏
页数:7
相关论文
共 50 条
  • [11] Cross-Talk of Signaling Pathways in the Pathogenesis of Allergic Asthma and Cataract
    Zhao, Yang
    Liu, Sumei
    Li, Xiangsheng
    Xu, Zhenzhen
    Hao, Lifang
    Cui, Zhe
    Bi, Kewei
    Zhang, Yanfen
    Liu, Zhongcheng
    PROTEIN AND PEPTIDE LETTERS, 2020, 27 (09): : 810 - 822
  • [12] Allergens and environmental factors in allergic respiratory diseases
    Munir, AKM
    PEDIATRIC PULMONOLOGY, 1997, : 17 - 18
  • [13] Exposure to environmental factors and relationship to allergic rhinitis and/or asthma
    Azalim, Silvia P.
    Camargos, Paulo
    Alves, Antonio L.
    Senna, Maria Ines B.
    Sakurai, Emilia
    Keller, Wilfrid Schwabe
    ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE, 2014, 21 (01) : 59 - 63
  • [14] Prevalence of asthma and allergic diseases in Sanliurfa, Turkey, and the relation to environmental and socioeconomic factors: Is the hygiene hypothesis enough?
    Zeyrek, C. D.
    Zeyrek, F.
    Sevinc, E.
    Demir, E.
    JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, 2006, 16 (05) : 290 - 295
  • [15] Psoriasis and Cardiovascular Diseases: An Immune-Mediated Cross Talk?
    Orlando, Gloria
    Molon, Barbara
    Viola, Antonella
    Alaibac, Mauro
    Angioni, Roberta
    Piaserico, Stefano
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [16] Exploiting the innate immune system to control allergic asthma
    Dombrowicz, D
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2005, 35 (10) : 2786 - 2788
  • [17] Allergic asthma and the developing immune system: a pilot study
    Pucheu-Haston, C. M.
    Copeland, L. B.
    Ward, M. D. W.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (02) : S181 - S181
  • [18] Out-door environmental factors and allergic diseases
    Piekarska, B.
    Furmanczyk, K.
    Lipiec, A.
    Walkiewicz, A.
    Raciborski, F.
    Samolinski, B.
    ALLERGY, 2009, 64 : 322 - 322
  • [19] Risk Factors for Asthma and Other Allergic Diseases in Seasonal Rhinitis
    Celikel, Serhat
    Isik, Sacide Rana
    Demir, Ahmet Ugur
    Karakaya, Gul
    Kalyoncu, Ali Fuat
    JOURNAL OF ASTHMA, 2008, 45 (08) : 710 - 714
  • [20] Probiotics function and modulation of the immune system in allergic diseases
    Eslami, M.
    Bahar, A.
    Keikha, M.
    Karbalaei, M.
    Kobyliak, N. M.
    Yousefi, B.
    ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2020, 48 (06) : 771 - 788