Four New Phenolic Glycosides from the Seeds of Lepidium apetalum

被引：1

作者：

Li, Meng ^{[1
,2
]}

Zhang, Jingke ^{[1
,2
]}

Wang, Xiaolan ^{[1
,2
]}

Zhang, Li ^{[1
,2
]}

Sun, Yanjun ^{[1
,2
]}

Chen, Hui ^{[1
,2
]}

Feng, Weisheng ^{[1
,2
]}

Zheng, Xiaoke ^{[1
,2
]}

机构：

[1] Henan Univ Chinese Med, P, R China, Zhengzhou 450046, Peoples R China

[2] Engn& Technol Ctr Chinese Medicine Dev Henan Prov, Zhengzhou 450046, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Lepidium apetalum Willd; seeds; phenolic glycosides; cardiocytes; protective effects; NRK52E CELLS; DERIVATIVES; WILLD;

D O I：

10.1007/s10600-023-04039-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new phenolic glycosides lepidiumosides A-D (1-4) were isolated from the water extract of the seeds of Lepidium apetalum Willd. Their structures were determined by extensive spectroscopic (UV, IR, HR-ESI-MS, 1D and 2D NMR) analyses. In addition, these compounds were evaluated for their protective effects impaired by H2O2 in H9c2 cells, suggesting that compounds 1-4 exhibited protective effects against H2O2-induced cardiotoxicity.

引用

页码：515 / 519

页数：5

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