Four New Phenolic Glycosides from the Seeds of Lepidium apetalum

被引：1
|
作者：
Li, Meng [1 ,2 ]
Zhang, Jingke [1 ,2 ]
Wang, Xiaolan [1 ,2 ]
Zhang, Li [1 ,2 ]
Sun, Yanjun [1 ,2 ]
Chen, Hui [1 ,2 ]
Feng, Weisheng [1 ,2 ]
Zheng, Xiaoke [1 ,2 ]
机构：
[1] Henan Univ Chinese Med, P, R China, Zhengzhou 450046, Peoples R China
[2] Engn& Technol Ctr Chinese Medicine Dev Henan Prov, Zhengzhou 450046, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Lepidium apetalum Willd; seeds; phenolic glycosides; cardiocytes; protective effects; NRK52E CELLS; DERIVATIVES; WILLD;
D O I：
10.1007/s10600-023-04039-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Four new phenolic glycosides lepidiumosides A-D (1-4) were isolated from the water extract of the seeds of Lepidium apetalum Willd. Their structures were determined by extensive spectroscopic (UV, IR, HR-ESI-MS, 1D and 2D NMR) analyses. In addition, these compounds were evaluated for their protective effects impaired by H2O2 in H9c2 cells, suggesting that compounds 1-4 exhibited protective effects against H2O2-induced cardiotoxicity.
引用
收藏
页码：515 / 519
页数：5
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